EP 1309728 A2 20030514 - METHOD FOR THE HIGHLY PARALLEL ANALYSIS OF METHYLATION STATUS
Title (en)
METHOD FOR THE HIGHLY PARALLEL ANALYSIS OF METHYLATION STATUS
Title (de)
VERFAHREN ZUR HOCHPARALLELEN ANALYSE VON METHYLIERUNGSSTATUS
Title (fr)
PROCEDE D'ANALYSE HAUTEMENT PARALLELE D'ETAT DE METHYLATION
Publication
Application
Priority
- DE 0101607 W 20010425
- DE 10021204 A 20000425
Abstract (en)
[origin: WO0181620A2] The invention relates to a method for the highly parallel characterization of polymorphisms, especially SNPs, which can be used for the simultaneous or separate detection of DNA methylations. A set of probes that is provided with at least one detectable marking characteristic of the corresponding probe is bound to an addressed surface, the bond of the probes to the surface being photochemically, chemically or enzymatically cleavable. A nucleic acid to be analyzed is then bound to said probes, the probes are modified in an allele-specific enzymatic reaction and a part of the probes that is irrelevant for the analysis of the allele-specific reaction is removed. The allele-specific products are analyzed by means of the detectable markings and the alleles present in the analyzed nucleic acid probe are determined.
IPC 1-7
IPC 8 full level
C12Q 1/68 (2006.01); C12Q 1/6827 (2018.01)
CPC (source: EP)
C12Q 1/6827 (2013.01)
Citation (search report)
See references of WO 0181620A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated extension state (EPC)
AL LT LV MK RO SI
DOCDB simple family (publication)
WO 0181620 A2 20011101; WO 0181620 A3 20030213; AU 6575901 A 20011107; DE 10021204 A1 20011108; DE 10191554 D2 20030612; EP 1309728 A2 20030514
DOCDB simple family (application)
DE 0101607 W 20010425; AU 6575901 A 20010425; DE 10021204 A 20000425; DE 10191554 T 20010425; EP 01942981 A 20010425