EP 1310506 A4 20040414 - PROCESS FOR PRODUCING ERYTHROMYCIN DERIVATIVE
Title (en)
PROCESS FOR PRODUCING ERYTHROMYCIN DERIVATIVE
Title (de)
VERFAHREN ZUR HERSTELLUNG EINES ERYTHROMYCINDERIVATES
Title (fr)
PROCEDE SERVANT A PREPARER UN DERIVE D'ERYTHROMYCINE
Publication
Application
Priority
- JP 0106928 W 20010810
- JP 2000245850 A 20000814
Abstract (en)
[origin: EP1310506A1] There is provided a preparation process useful for an efficient synthesis of 6-O-substituted ketolide derivatives by combining a characterized step of introduction of a substituent at the 6-position by selective cleavage of a C-O bond of the cyclic acetal at the 9-position side via 6,9-cyclic acetal 5-O-desosaminyl erythronolide derivative, a step of conversion into carbonyl groups at the 9- and 3-positions, and a step of 11,12-cyclic carbamation to lead to 6-O-substituted ketolide derivatives.
IPC 1-7
IPC 8 full level
C07H 17/08 (2006.01)
CPC (source: EP KR US)
C07H 17/08 (2013.01 - EP KR US)
Citation (search report)
[A] OR ET AL: "DESIGN, SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF 6-O-SUBSTITUTED KETOLIDES ACTIVE AGAINST RESISTANT RESPIRATORY TRACT PATHOGENS", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, vol. 43, March 2000 (2000-03-01), pages 1045 - 1049, XP002194138, ISSN: 0022-2623
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
EP 1310506 A1 20030514; EP 1310506 A4 20040414; AU 7776401 A 20020225; CA 2417319 A1 20030127; CN 1197870 C 20050420; CN 1446224 A 20031001; HK 1057047 A1 20040312; KR 20030024859 A 20030326; TW I225067 B 20041211; US 2003191295 A1 20031009; US 6713615 B2 20040330; WO 0214339 A1 20020221
DOCDB simple family (application)
EP 01955675 A 20010810; AU 7776401 A 20010810; CA 2417319 A 20010810; CN 01814114 A 20010810; HK 03109370 A 20031224; JP 0106928 W 20010810; KR 20037002087 A 20030213; TW 90119687 A 20010810; US 34452903 A 20030212