EP 1311656 A1 20030521 - USE OF BIOACTIVE GLASS COMPOSITIONS TO STIMULATE OSTEOBLAST PRODUCTION
Title (en)
USE OF BIOACTIVE GLASS COMPOSITIONS TO STIMULATE OSTEOBLAST PRODUCTION
Title (de)
VERWENDUNG VON BIOAKTIVEN GLASZUSAMMENSETZUNGEN ZUR STIMULIERUNG DER OSTEOBLASTPRODUKTION
Title (fr)
UTILISATION DE COMPOSITIONS DE VERRE BIOACTIF POUR LA STIMULATION DE LA PRODUCTION D'OSTEOBLASTE
Publication
Application
Priority
- US 0121801 W 20010711
- US 21746000 P 20000711
Abstract (en)
[origin: WO0204606A1] Compositions comprising bioactive glass compositions or extracts thereof which include ions in an appropriate concentration and ratio that they enhance osteoblast production, and methods of preparation and use thereof, are disclosed. The compositions can be included in implantable devices that are capable of inducing tissue formation in autogeneic, allogeneic and xenogeneic implants, for example as coatings and/or matrix materials. Examples of such devices include prosthetic implants, sutures, stents, screws, plates, tubes, and the like. Aqueous extracts of the bioactive glass compositions, which extracts are capable of stimulating osteoblast production, are also disclosed. The compositions can be used, for example, to induce local tissue formation from a progenitor cell in a mammal, for accelerating allograft repair in a mammal, for promoting in vivo integration of an implantable prosthetic device to enhance the bond strength between the prosthesis and the existing target tissue at the joining site, and for treating tissue degenerative conditions.
IPC 1-7
IPC 8 full level
A61L 27/10 (2006.01); A01N 63/00 (2006.01); A61K 45/06 (2006.01); A61L 17/00 (2006.01); A61L 27/32 (2006.01); A61L 31/02 (2006.01); A61L 31/08 (2006.01); C03C 3/097 (2006.01); C03C 4/00 (2006.01); C03C 12/00 (2006.01); C12N 5/00 (2006.01); C12N 5/077 (2010.01); A61K 35/12 (2015.01)
CPC (source: EP)
A61K 45/06 (2013.01); A61L 27/10 (2013.01); A61L 31/02 (2013.01); C03C 3/097 (2013.01); C03C 4/0007 (2013.01); C03C 4/0014 (2013.01); C03C 12/00 (2013.01); C12N 5/0068 (2013.01); C12N 5/0654 (2013.01); A61K 35/12 (2013.01); A61L 2430/02 (2013.01); C12N 2533/12 (2013.01)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated extension state (EPC)
AL LT LV MK RO SI
DOCDB simple family (publication)
WO 0204606 A1 20020117; AU 8050701 A 20020121; CA 2414510 A1 20020117; EP 1311656 A1 20030521; EP 1311656 A4 20090506
DOCDB simple family (application)
US 0121801 W 20010711; AU 8050701 A 20010711; CA 2414510 A 20010711; EP 01958900 A 20010711