EP 1313475 A4 20040818 - ANTI-CANCER COMPOSITION COMPOSED OF ANTI-CANCER AND ANTI-MALARIAL DRUGS
Title (en)
ANTI-CANCER COMPOSITION COMPOSED OF ANTI-CANCER AND ANTI-MALARIAL DRUGS
Title (de)
KREBSHEILMITTEL-ZUSAMMENSTELLUNG BESTEHEND AUS KREBSHEILMITTELN UND ANTI-MALARIA HEILMITTELN
Title (fr)
COMPOSITION ANTICANCEREUSE CONSTITUEE DE MEDICAMENTS ANTICANCEREUX ET DE MEDICAMENTS ANTIPALUDIQUES
Publication
Application
Priority
- KR 0101314 W 20010802
- KR 20000044851 A 20000802
Abstract (en)
[origin: WO0213826A1] The present invention relates to complex compositions of anticancer drugs, which are administrated in combination with antimalarial drugs for reducing a minimum IC50 of anticancer drugs and inhibiting development of drug resistance of cancer cells caused by anticancer drugs, thereby enhancing the effect of the anticancer drugs. More particularly, the present invention relates to complex compositions of anticancer drugs, which are administrated in combination with antimalarial drugs for a minimun IC50 of anticancer drugs and inhibiting development of drug resistance of cancer cells caused by anticancer drugs, thereby enhancing the effect of the anticancer drugs; in which the anticancer drugs are selected from the group consisting of doxorubicin, cisplatin, and the like and the antimalarial drugs are selected from the group consisting of hydroxchloroquine, chloroquine, primaquine and the like.
IPC 1-7
A61K 31/47; A61K 31/282; A61K 31/70; A61K 31/4706; A61P 35/00
IPC 8 full level
A61K 33/00 (2006.01); A61K 31/47 (2006.01); A61K 31/704 (2006.01); A61K 33/243 (2019.01)
CPC (source: EP KR US)
A61K 31/47 (2013.01 - EP); A61K 31/704 (2013.01 - EP); A61K 33/00 (2013.01 - KR); A61K 33/243 (2018.12 - EP US); A61P 35/00 (2017.12 - EP)
Citation (search report)
- [X] BARTOLI KLUGMANN, F. ET AL.: "Effect of lysosomotropic and membrane active substances on adriamycin uptake and histamine release", ANTICANCER RESEARCH, vol. 10, 1990, pages 1571 - 1578, XP009032654
- [X] SHIRAISHI, N. ET AL.: "Lysosomotropic agents reverse multiple drug resistance in human cancer cells", CANCER LETTERS, vol. 30, 1986, pages 251 - 259, XP009032506
- [X] COLE, S.P.C. ET AL.: "Effect of calcium antagonists on the chemosensitivityof two multidrug resistant human tumour cell lines which do not overexpress P-glycoprotein", BRITISH JOURNAL OF CANCER, vol. 59, 1989, pages 42 - 46, XP009032653
- [X] KUWANO, M.: "a basic study to circumvent resistance to anticancer agents", NISHINIHON JOURNAL OF UROLOGY, vol. 48, no. 1, 1986, pages 1 - 7, XP009032660
- See references of WO 0213826A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0213826 A1 20020221; WO 0213826 A9 20031113; AU 7582101 A 20020225; EP 1313475 A1 20030528; EP 1313475 A4 20040818; KR 100390332 B1 20030707; KR 20020011528 A 20020209
DOCDB simple family (application)
KR 0101314 W 20010802; AU 7582101 A 20010802; EP 01953364 A 20010802; KR 20000044851 A 20000802