EP 1315707 A1 20030604 - LIPO- OR AMPHIPHILIC SCINTILLATORS AND THEIR USE IN ASSAYS
Title (en)
LIPO- OR AMPHIPHILIC SCINTILLATORS AND THEIR USE IN ASSAYS
Title (de)
LIPO- ODER AMPHIPHILE SCINTILLATOREN UND IHRE VERWENDUNG IN ASSAYS
Title (fr)
SCINTILLATEURS LIPOPHILES OU AMPHIPHILES ET LEUR UTILISATION POUR DES BIOANALYSES
Publication
Application
Priority
- GB 0103695 W 20010817
- GB 0020503 A 20000818
- US 24799400 P 20001114
Abstract (en)
[origin: WO0214290A1] The invention provides scintillator molecules, consisting of one or more X moieties, which is a phosphor, covalently attached to one or more R<1> moieties which is a lipophilic or amphiphilic group, wherein the scintillator molecule is capable of integrating into a cell, a cell membrane, a biological membrane, an artificial membrane or a delivery vehicle and when integrated can act as a phosphor. Preferred seintillator molecules are of formula. Also provided are liposomes or micelles containing the novel scintillator compounds, methods for preparing the liposomes or micelles containing the novel scintillator compounds and the use of the liposomes or micelles as delivery vehicles to insert the scintillator compounds into the cell membranes of cells. In addition, the invention provides cells containing the novel scintillator compounds and the use of the cells in assay systems.
IPC 1-7
IPC 8 full level
C07D 263/32 (2006.01); C09K 11/06 (2006.01); G01N 33/50 (2006.01); G01N 33/58 (2006.01); G01N 33/92 (2006.01); G01T 1/20 (2006.01); G01T 1/204 (2006.01)
CPC (source: EP KR)
C07D 263/32 (2013.01 - EP); C09K 11/06 (2013.01 - KR); G01N 33/5008 (2013.01 - EP); G01N 33/502 (2013.01 - EP); G01N 33/58 (2013.01 - EP); G01N 33/92 (2013.01 - EP)
Citation (search report)
See references of WO 0214290A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0214290 A1 20020221; AU 7863301 A 20020225; BR 0113328 A 20030729; CA 2420006 A1 20020221; CN 1458925 A 20031126; EP 1315707 A1 20030604; GB 0306216 D0 20030423; GB 2383329 A 20030625; IL 154485 A0 20030917; JP 2004506754 A 20040304; KR 20030066601 A 20030809
DOCDB simple family (application)
GB 0103695 W 20010817; AU 7863301 A 20010817; BR 0113328 A 20010817; CA 2420006 A 20010817; CN 01815712 A 20010817; EP 01956714 A 20010817; GB 0306216 A 20010817; IL 15448501 A 20010817; JP 2002519433 A 20010817; KR 20037002383 A 20030218