EP 1315821 A2 20030604 - REPORTER SYSTEM FOR CELL SURFACE RECEPTOR-LIGAND BINDING
Title (en)
REPORTER SYSTEM FOR CELL SURFACE RECEPTOR-LIGAND BINDING
Title (de)
REPORTERSYSTEM DER ZELLOBERFLÄCHENREZEPTOR-LIGANDEN-BINDUNG
Title (fr)
SYSTEME REPORTER POUR LIAISON LIGAND-RECEPTEUR DE SURFACE CELLULAIRE
Publication
Application
Priority
- IB 0101938 W 20010906
- US 23070500 P 20000907
Abstract (en)
[origin: WO0220749A2] The present invention provides chimeric reporter constructs, recombinant cells containing the reporter constructs, and assays utilizing the recombinant cells for detection of substances that interact with cell surface receptors, such as those of the G-protein coupled receptor family. The reporer constructs and recombinant cells are particularly well suited for high-throughput screening assays, and detection of interaction between a substance and a cell surface receptor can be performed visually, by FACS, or by luminometry.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); C12N 5/10 (2006.01); C12N 15/65 (2006.01); C12Q 1/02 (2006.01); C12Q 1/68 (2006.01); C12Q 1/6897 (2018.01)
CPC (source: EP US)
C12N 15/65 (2013.01 - EP US); C12Q 1/6897 (2013.01 - EP US); G01N 2333/726 (2013.01 - EP US)
Citation (search report)
See references of WO 0220749A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0220749 A2 20020314; WO 0220749 A3 20030313; AU 9412001 A 20020322; CA 2421858 A1 20020314; EP 1315821 A2 20030604; JP 2004508042 A 20040318; US 2002150912 A1 20021017
DOCDB simple family (application)
IB 0101938 W 20010906; AU 9412001 A 20010906; CA 2421858 A 20010906; EP 01974607 A 20010906; JP 2002525756 A 20010906; US 94633401 A 20010906