Global Patent Index - EP 1315830 A2

EP 1315830 A2 2003-06-04 - COMPOSITIONS AND METHODS FOR TARGETING PEPTIDES IN HUMANS IN VIVO

Title (en)

COMPOSITIONS AND METHODS FOR TARGETING PEPTIDES IN HUMANS IN VIVO

Title (de)

ZUSAMMENSETZUNGEN UND VERFAHREN ZUR ZIELGERICHTETEN, IN VIVO EINBRINGUNG VON PEPTIDEN IN DEN MENSCHEN

Title (fr)

COMPOSITIONS ET PROCEDES SE RAPPORANT A DES PEPTIDES CIBLANTS CHEZ L'HOMME IN VIVO

Publication

EP 1315830 A2 (EN)

Application

EP 01970681 A

Priority

  • US 0128044 W
  • US 23126600 P
  • US 76510101 A

Abstract (en)

[origin: WO0220822A2] The present invention concerns novel methods of identifying peptide sequences that selectively bind to targets. In alternative embodiments, targets may comprise cells or clumps of cells, particles attached to chemicals compounds, molecules or aggregates, or parasites. In preferred embodiments, target cells are sorted before exposure to the phage library. The general method, Biopanning and Rapid Analysis of Selective Interactive Ligands (BRASIL) provides for rapid and efficient separation of phage that bind to targets, while preserving unbound phage. BRASIL may be used in preselection procedure to subract phage that bind non-specifically to a first target before exposing the subtracted library to a second target. Certain embodiments concern targeting peptides identified by BRASIL and methods of use of such peptides for targeted delivera of therapeutic agents or imaging agents or diagnosis or treatment of diseases. Novel compositions comprising a first phase, second phase, target and a phage library are also disclosed.

IPC 1-7 (main, further and additional classification)

C12Q 1/02; A61K 49/00; A61K 49/14; C12N 5/00; C12N 5/08; C12N 7/02; C12N 15/07; C12N 15/09; C12N 15/10; C12P 21/00; C12Q 1/24; C12Q 1/70; G01N 33/50

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); A61K 31/225 (2006.01); A61K 31/23 (2006.01); A61K 31/56 (2006.01); A61K 31/683 (2006.01); A61K 31/685 (2006.01); A61K 31/688 (2006.01); A61K 31/713 (2006.01); A61K 35/12 (2006.01); A61K 35/76 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01); A61K 39/02 (2006.01); A61K 39/12 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61K 47/42 (2006.01); A61K 47/48 (2006.01); A61K 48/00 (2006.01); A61K 49/00 (2006.01); A61P 3/10 (2006.01); A61P 7/00 (2006.01); A61P 9/00 (2006.01); A61P 9/10 (2006.01); A61P 13/02 (2006.01); A61P 19/02 (2006.01); A61P 25/28 (2006.01); A61P 29/00 (2006.01); A61P 31/04 (2006.01); A61P 31/10 (2006.01); A61P 31/12 (2006.01); A61P 31/18 (2006.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01); A61P 37/02 (2006.01); A61P 37/04 (2006.01); A61P 43/00 (2006.01); C07K 1/04 (2006.01); C07K 5/08 (2006.01); C07K 5/10 (2006.01); C07K 7/04 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); C07K 14/00 (2006.01); C07K 14/005 (2006.01); C07K 14/47 (2006.01); C07K 14/52 (2006.01); C07K 16/08 (2006.01); C07K 16/18 (2006.01); C07K 19/00 (2006.01); C12N 7/02 (2006.01); C12N 15/10 (2006.01); C12N 15/861 (2006.01); C12N 15/864 (2006.01); C12Q 1/02 (2006.01); C12Q 1/70 (2006.01); G01N 33/50 (2006.01); G01N 33/53 (2006.01); G01N 33/566 (2006.01)

CPC (invention and additional information)

C07K 14/52 (2013.01); C07K 1/047 (2013.01); C07K 7/06 (2013.01); C12N 15/1037 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01); A61K 2039/5256 (2013.01); C12N 2810/40 (2013.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

EPO simple patent family

WO 0220822 A2 20020314; WO 0220822 A3 20020627; AT 478141 T 20100915; CA 2421191 A1 20020314; CA 2421195 A1 20020314; CA 2421200 A1 20020314; CA 2421271 A1 20020314; CA 2421380 A1 20020314; DE 60142840 D1 20100930; EP 1315512 A2 20030604; EP 1315512 A4 20051109; EP 1315830 A2 20030604; EP 1315830 A4 20051019; EP 1315840 A2 20030604; EP 1315840 A4 20051102; EP 1315965 A2 20030604; EP 1315965 A4 20060405; EP 1322755 A1 20030702; EP 1322755 A4 20060405; EP 1322755 B1 20100818; EP 2028187 A1 20090225; JP 2004515751 A 20040527; JP 2004530404 A 20041007; JP 2004533803 A 20041111; JP 2004536020 A 20041202; JP 2011120587 A 20110623; JP 2012065662 A 20120405; JP 5591209 B2 20140917; PT 1322755 E 20101119; WO 0220722 A2 20020314; WO 0220722 A3 20030206; WO 0220722 A9 20030821; WO 0220723 A2 20020314; WO 0220723 A3 20020829; WO 0220724 A2 20020314; WO 0220724 A3 20020711

INPADOC legal status


2006-05-31 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20051115

2005-10-19 [A4] SUPPLEMENTARY SEARCH REPORT

- Effective date: 20050901

2005-06-01 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 12Q 1/02 A

2005-06-01 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 12Q 1/24 B

2005-06-01 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 12Q 1/70 B

2005-06-01 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 12P 21/00 B

2005-06-01 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 12N 5/00 B

2005-06-01 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 12N 5/08 B

2005-06-01 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 12N 7/02 B

2005-06-01 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 12N 15/07 B

2005-06-01 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 12N 15/09 B

2005-06-01 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7A 61K 49/00 B

2005-06-01 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7A 61K 49/14 B

2005-06-01 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 12N 15/10 B

2005-06-01 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7G 01N 33/50 B

2003-06-04 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20030306

2003-06-04 [AK] DESIGNATED CONTRACTING STATES:

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

2003-06-04 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Countries: AL LT LV MK RO SI