EP 1317433 A2 20030611 - INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3
Title (en)
INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3
Title (de)
INHIBITOREN VON GLYCOGEN SYNTHASE KINASE 3
Title (fr)
INHIBITEURS DE GLYCOGENE-SYNTHASE KINASE 3
Publication
Application
Priority
- US 0142081 W 20010906
- US 23048000 P 20000906
Abstract (en)
[origin: WO0220495A2] New pyrimidine or pyridine based compounds, compositions and methods of inhibiting the activity of glycogen synthase kinase (GSK3) <i>in vitro</i> and of treatment of GSK3 mediated disorders <i>in vivo</i> are provided. The methods, compounds and compositions of the invention may be employed alone, or in combination with other pharmacologically active agents in the treatment of disorders mediated by GSK3 activity, such as diabetes, Alzheimer's disease and other neurodegenerative disorders, obesity, atherosclerotic cardiovascular disease, essential hypertension, polycystic ovary syndrome, syndrome X, ischemia, traumatic brain injury, bipolar disorder, immunodeficiency or cancer.
IPC 1-7
C07D 239/42; C07D 401/12; C07D 405/12; C07D 403/12; C07D 405/14; C07D 413/14; C07D 401/14; C07D 213/85; C07D 213/75; C07D 213/74; C07D 213/80; A61K 31/505; A61P 25/28
IPC 8 full level
A61K 31/444 (2006.01); A61K 31/496 (2006.01); A61K 31/505 (2006.01); A61K 31/506 (2006.01); A61K 31/519 (2006.01); A61K 31/5377 (2006.01); A61P 3/04 (2006.01); A61P 3/10 (2006.01); A61P 9/10 (2006.01); A61P 9/12 (2006.01); A61P 15/00 (2006.01); A61P 25/00 (2006.01); A61P 25/18 (2006.01); A61P 25/24 (2006.01); A61P 25/28 (2006.01); A61P 35/00 (2006.01); A61P 37/04 (2006.01); A61P 43/00 (2006.01); C07D 213/64 (2006.01); C07D 213/74 (2006.01); C07D 213/75 (2006.01); C07D 213/80 (2006.01); C07D 213/85 (2006.01); C07D 231/12 (2006.01); C07D 233/60 (2006.01); C07D 235/06 (2006.01); C07D 239/42 (2006.01); C07D 401/04 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 403/12 (2006.01); C07D 403/14 (2006.01); C07D 405/12 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01); C07D 413/14 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); C12N 1/38 (2006.01); C12N 9/99 (2006.01)
CPC (source: EP KR)
A61P 3/04 (2017.12 - EP); A61P 3/10 (2017.12 - EP); A61P 9/10 (2017.12 - EP); A61P 9/12 (2017.12 - EP); A61P 15/00 (2017.12 - EP); A61P 25/00 (2017.12 - EP); A61P 25/18 (2017.12 - EP); A61P 25/24 (2017.12 - EP); A61P 25/28 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 37/04 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07D 213/74 (2013.01 - EP); C07D 213/75 (2013.01 - EP); C07D 213/80 (2013.01 - EP); C07D 213/85 (2013.01 - EP); C07D 239/42 (2013.01 - EP KR); C07D 401/12 (2013.01 - EP); C07D 401/14 (2013.01 - EP); C07D 403/12 (2013.01 - EP); C07D 405/12 (2013.01 - EP); C07D 405/14 (2013.01 - EP); C07D 413/14 (2013.01 - EP)
Citation (search report)
See references of WO 0220495A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0220495 A2 20020314; WO 0220495 A3 20020620; AU 2001295026 B2 20080403; AU 9502601 A 20020322; CN 100506801 C 20090701; CN 1592743 A 20050309; EP 1317433 A2 20030611; HK 1072936 A1 20050916; JP 2004514656 A 20040520; KR 100816769 B1 20080326; KR 100860827 B1 20080930; KR 20040030404 A 20040409; KR 20080013026 A 20080212
DOCDB simple family (application)
US 0142081 W 20010906; AU 2001295026 A 20010906; AU 9502601 A 20010906; CN 01818425 A 20010906; EP 01975734 A 20010906; HK 05104683 A 20050603; JP 2002525117 A 20010906; KR 20037003327 A 20030306; KR 20087001887 A 20080124