Global Patent Index - EP 1320533 A1

EP 1320533 A1 2003-06-25 - PRODRUGS OF A 7-ACYLAMINO-3-HETEROARYLTHIO-3-CEPHEM CARBOXYLIC ACID ANTIBIOTIC

Title (en)

PRODRUGS OF A 7-ACYLAMINO-3-HETEROARYLTHIO-3-CEPHEM CARBOXYLIC ACID ANTIBIOTIC

Title (de)

PRO-ARZNEIMITTEL EINES 7-ACYLAMINO-3-HETEROARYLTHIO-3-CEPHEM CARBONSÄUREANTIBIOTIKUMS

Title (fr)

PROMEDICAMENTS D'UN ANTIBIOTIQUE A BASE D'ACIDE 7-ACYLAMINO-3-HETEROARYLTHIO-3-CEPHEM CARBOXYLIQUE

Publication

EP 1320533 A1 (EN)

Application

EP 01918879 A

Priority

  • US 0108980 W
  • US 66872200 A

Abstract (en)

[origin: WO0224708A1] The present invention relates to prodrugs of the antibiotic compound (7R)-7-[(Z)-2-(2-amino-5-chlorothiazol-4-yl)-2-(hydroxylimino)acetamido]acetamidol]-3-{3-(2-aminoethylthiomethyl]-pyrid-4-ylthio}-3-cephem-4-carbocyllic acid, where the prodrugs are substantially more water soluble at or near neutral pH than the parent compound.

IPC 1-7 (main, further and additional classification)

C07D 501/59; A61K 31/546; A61P 31/04

IPC 8 full level (invention and additional information)

A61K 31/546 (2006.01); A61P 31/04 (2006.01); A61P 43/00 (2006.01); C07D 501/00 (2006.01); C07D 501/59 (2006.01)

CPC (invention and additional information)

C07D 501/00 (2013.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

EPO simple patent family

WO 0224708 A1 20020328; AU 2001245902 B2 20070823; AU 4590201 A 20020402; BR 0114058 A 20030722; CA 2423334 A1 20020328; CN 1535275 A 20041006; EP 1320533 A1 20030625; EP 1320533 A4 20041215; IL 154883 D0 20031031; JP 2004525862 A 20040826; MX PA03002456 A 20030619; NO 20031275 A 20030521; NO 20031275 D0 20030319; NZ 525401 A 20051028; RU 2279435 C2 20060710; ZA 200302127 B 20070725

INPADOC legal status


2010-03-31 [18D] APPLICATION DEEMED TO BE WITHDRAWN

- Effective date: 20091001

2008-02-20 [RAP1] TRANSFER OF RIGHTS OF AN APPLICATION

- Owner name: CALKINS, TREVOR

2008-02-20 [RAP1] TRANSFER OF RIGHTS OF AN APPLICATION

- Owner name: LEE, VING J.

2008-02-20 [RAP1] TRANSFER OF RIGHTS OF AN APPLICATION

- Owner name: TRINE PHARMACEUTICALS, INC.

2008-02-20 [RAP1] TRANSFER OF RIGHTS OF AN APPLICATION

- Owner name: HECKER, SCOTT J.

2008-02-20 [RAP1] TRANSFER OF RIGHTS OF AN APPLICATION

- Owner name: CHO, AESOP

2008-02-20 [RAP1] TRANSFER OF RIGHTS OF AN APPLICATION

- Owner name: GLINKA, TOMASZ W.

2004-12-15 [A4] DESPATCH OF SUPPLEMENTARY SEARCH REPORT

- Effective date: 20041028

2003-06-25 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20030414

2003-06-25 [AK] DESIGNATED CONTRACTING STATES:

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

2003-06-25 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO:

- Countries: AL LT LV MK RO SI