EP 1322322 A2 20030702 - COMPOUNDS AND METHODS FOR INHIBITING ALPHA-1 BETA-1 INTEGRINS
Title (en)
COMPOUNDS AND METHODS FOR INHIBITING ALPHA-1 BETA-1 INTEGRINS
Title (de)
VERBINDUNGEN UND METHODEN ZUR HEMMUNG VON ALPHA-1-BETA-1-INTEGRINEN
Title (fr)
COMPOSES ET PROCEDES POUR L'INHIBITION D'INTEGRINES ALPHA-1 BETA-1
Publication
Application
Priority
- US 0128522 W 20010912
- US 23159100 P 20000911
Abstract (en)
[origin: WO0222571A2] Obtustatin is a novel, RGD-independent short disintegrin that potently and selectively inhibits the binding of alpha 1 beta 1 integrin to its adhesive ligand. Obtustatin, and fragments, derivatives, homologs and analogs of obtustatin may be used to treat diseases and modulate biological conditions associated with alpha 1 beta 1 integrin.
IPC 1-7
A61K 38/04; A61K 38/05; A61K 38/06; A61K 38/07; A61K 38/08; A61K 38/09; A61K 38/10; A61K 38/16; A61K 38/17; C07K 5/04; C07K 5/06; C12N 15/10; C07K 5/08; C07K 5/10; C07K 14/46
IPC 8 full level
A61P 7/12 (2006.01); A61P 9/10 (2006.01); A61P 21/04 (2006.01); C07K 5/06 (2006.01); C07K 5/068 (2006.01); C07K 5/097 (2006.01); C07K 5/103 (2006.01); C07K 14/46 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP)
A61P 7/12 (2017.12); A61P 9/10 (2017.12); A61P 21/04 (2017.12); C07K 5/0606 (2013.01); C07K 5/06086 (2013.01); C07K 5/0821 (2013.01); C07K 5/1013 (2013.01); C07K 14/46 (2013.01); A61K 38/00 (2013.01)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0222571 A2 20020321; WO 0222571 A3 20020620; AU 9455201 A 20020326; CA 2421786 A1 20020321; EP 1322322 A2 20030702; EP 1322322 A4 20050406
DOCDB simple family (application)
US 0128522 W 20010912; AU 9455201 A 20010912; CA 2421786 A 20010912; EP 01975200 A 20010912