Global Patent Index - EP 1322322 A4

EP 1322322 A4 20050406 - COMPOUNDS AND METHODS FOR INHIBITING ALPHA-1 BETA-1 INTEGRINS

Title (en)

COMPOUNDS AND METHODS FOR INHIBITING ALPHA-1 BETA-1 INTEGRINS

Title (de)

VERBINDUNGEN UND METHODEN ZUR HEMMUNG VON ALPHA-1-BETA-1-INTEGRINEN

Title (fr)

COMPOSES ET PROCEDES POUR L'INHIBITION D'INTEGRINES ALPHA-1 BETA-1

Publication

EP 1322322 A4 20050406 (EN)

Application

EP 01975200 A 20010912

Priority

  • US 0128522 W 20010912
  • US 23159100 P 20000911

Abstract (en)

[origin: WO0222571A2] Obtustatin is a novel, RGD-independent short disintegrin that potently and selectively inhibits the binding of alpha 1 beta 1 integrin to its adhesive ligand. Obtustatin, and fragments, derivatives, homologs and analogs of obtustatin may be used to treat diseases and modulate biological conditions associated with alpha 1 beta 1 integrin.

IPC 1-7

A61K 38/04; A61K 38/05; A61K 38/06; A61K 38/07; A61K 38/08; A61K 38/09; A61K 38/10; A61K 38/16; A61K 38/17; C07K 5/04; C07K 5/06; C12N 15/10; C07K 5/08; C07K 5/10; C07K 14/46

IPC 8 full level

A61P 7/12 (2006.01); A61P 9/10 (2006.01); A61P 21/04 (2006.01); C07K 5/06 (2006.01); C07K 5/068 (2006.01); C07K 5/097 (2006.01); C07K 5/103 (2006.01); C07K 14/46 (2006.01); A61K 38/00 (2006.01)

CPC (source: EP)

A61P 7/12 (2017.12); A61P 9/10 (2017.12); A61P 21/04 (2017.12); C07K 5/0606 (2013.01); C07K 5/06086 (2013.01); C07K 5/0821 (2013.01); C07K 5/1013 (2013.01); C07K 14/46 (2013.01); A61K 38/00 (2013.01)

Citation (search report)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

DOCDB simple family (publication)

WO 0222571 A2 20020321; WO 0222571 A3 20020620; AU 9455201 A 20020326; CA 2421786 A1 20020321; EP 1322322 A2 20030702; EP 1322322 A4 20050406

DOCDB simple family (application)

US 0128522 W 20010912; AU 9455201 A 20010912; CA 2421786 A 20010912; EP 01975200 A 20010912