EP 1322325 A1 20030702 - INHIBITING HEPATITIS C VIRUS PROCESSING AND REPLICATION WITH HSP90 INHIBITORS
Title (en)
INHIBITING HEPATITIS C VIRUS PROCESSING AND REPLICATION WITH HSP90 INHIBITORS
Title (de)
INHIBITION DER PROZESSIERUNG UND REPLIKATION DES HEPATITIS C VIRUS MIT HSP90-INHIBITOREN
Title (fr)
INHIBITION DE LA MATURATION ET DE LA REPLICATION DU VIRUS DE L'HEPATITE C AVEC INHIBITEURS DE HSP90
Publication
Application
Priority
- US 0122335 W 20010716
- US 21955000 P 20000720
Abstract (en)
[origin: WO0207761A1] The present invention features methods for inhibiting HCV replication and processing by targeting heat shock protein 90 (HSP90). HSP90 is a cellular chaperone protein that was found to be an essential factor in NS2/3 self-cleavage. HSP90 can be targeted using compounds inhibiting the ability of HSP90 to facilitate NS2/3 cleavage.
IPC 1-7
A61K 39/00; A61K 39/385; A01N 43/40; A01N 43/42; A61K 31/00; A61K 31/365; A61K 31/395
IPC 8 full level
A61K 31/00 (2006.01); A61K 31/365 (2006.01); A61K 31/395 (2006.01); A61K 45/00 (2006.01); A61P 31/12 (2006.01); A61P 31/14 (2006.01); A61P 43/00 (2006.01); C07D 225/06 (2006.01); C07D 313/00 (2006.01); G01N 33/15 (2006.01); G01N 33/50 (2006.01); G01N 33/53 (2006.01); G01N 33/566 (2006.01)
CPC (source: EP US)
A61K 31/00 (2013.01 - EP); A61K 31/365 (2013.01 - EP); A61K 31/395 (2013.01 - EP US); A61P 31/12 (2017.12 - EP); A61P 31/14 (2017.12 - EP); A61P 43/00 (2017.12 - EP)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0207761 A1 20020131; CA 2416603 A1 20030131; EP 1322325 A1 20030702; EP 1322325 A4 20040915; JP 2004504356 A 20040212
DOCDB simple family (application)
US 0122335 W 20010716; CA 2416603 A 20010716; EP 01952780 A 20010716; JP 2002513494 A 20010716