EP 1322602 A1 20030702 - SUBSTITUTED CINNAMIC ACID GUANIDIDES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AS A MEDICAMENT, AND TO A MEDICAMENT CONTAINING THESE COMPOUNDS
Title (en)
SUBSTITUTED CINNAMIC ACID GUANIDIDES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AS A MEDICAMENT, AND TO A MEDICAMENT CONTAINING THESE COMPOUNDS
Title (de)
SUBSTITUIERTE ZIMTSÄUREGUANIDIDE, VERFAHREN ZU IHRER HERSTELLUNG, IHRE VERWENDUNG ALS MEDIKAMENT SOWIE SIE ENTHALTENDES MEDIKAMENT
Title (fr)
GUANIDIDES D'ACIDE CINNAMIQUE SUBSTITUES, PROCEDES PERMETTANT DE LES PRODUIRE, LEUR UTILISATION COMME MEDICAMENT ET MEDICAMENT LES CONTENANT
Publication
Application
Priority
- DE 10046993 A 20000922
- EP 0110375 W 20010908
Abstract (en)
[origin: WO0224637A1] The invention relates to cinnamic acid guanidides, to a method for the production thereof, to their use as a medicament or diagnostic reagent, and to a medicament containing these compounds. According to the invention, compounds of formula (I), in which R(1), R(2), R(3), R(4), R(5), R(6), and R(7) have the meanings cited in the claims, are excellent cardiovascular therapeutic agents. These are obtained by reacting a compound of formula (II) with guanidine.
IPC 1-7
C07C 311/29; C07C 311/39; C07D 295/26; C07C 311/58; C07C 311/41; C07D 295/13; C07D 207/14; A61K 31/18; A61K 31/495; A61K 31/64
IPC 8 full level
C07D 295/12 (2006.01); A61K 31/18 (2006.01); A61K 31/40 (2006.01); A61K 31/495 (2006.01); A61P 9/06 (2006.01); A61P 9/10 (2006.01); A61P 43/00 (2006.01); C07C 303/40 (2006.01); C07C 311/29 (2006.01); C07C 311/39 (2006.01); C07C 311/41 (2006.01); C07C 311/58 (2006.01); C07D 207/14 (2006.01); C07D 295/13 (2006.01); C07D 295/22 (2006.01); C07D 295/26 (2006.01)
CPC (source: EP KR US)
A61P 9/06 (2017.12 - EP); A61P 9/10 (2017.12 - EP); A61P 41/00 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07C 311/29 (2013.01 - EP KR US); C07C 311/39 (2013.01 - EP US); C07C 311/41 (2013.01 - EP US); C07C 311/58 (2013.01 - EP US); C07D 207/14 (2013.01 - EP US); C07D 295/13 (2013.01 - EP US); C07D 295/26 (2013.01 - EP US)
Citation (search report)
See references of WO 0224637A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0224637 A1 20020328; AR 030947 A1 20030903; AU 9380201 A 20020402; BR 0114092 A 20030909; CA 2422709 A1 20030318; CN 1462268 A 20031217; CZ 2003815 A3 20030618; DE 10046993 A1 20020411; EE 200300110 A 20050415; EP 1322602 A1 20030702; HU P0303699 A2 20040428; HU P0303699 A3 20060228; IL 154953 A0 20031031; JP 2004509163 A 20040325; KR 20030094210 A 20031211; MX PA03002309 A 20030606; NO 20031273 D0 20030319; NO 20031273 L 20030514; PL 360993 A1 20040920; RU 2003111462 A 20041110; SK 3542003 A3 20030911; US 2002058710 A1 20020516; US 6399824 B1 20020604; ZA 200301778 B 20040416
DOCDB simple family (application)
EP 0110375 W 20010908; AR P010104445 A 20010920; AU 9380201 A 20010908; BR 0114092 A 20010908; CA 2422709 A 20010908; CN 01816055 A 20010908; CZ 2003815 A 20010908; DE 10046993 A 20000922; EE P200300110 A 20010908; EP 01974235 A 20010908; HU P0303699 A 20010908; IL 15495301 A 20010908; JP 2002529050 A 20010908; KR 20037004159 A 20030321; MX PA03002309 A 20010908; NO 20031273 A 20030319; PL 36099301 A 20010908; RU 2003111462 A 20010908; SK 3542003 A 20010908; US 95401601 A 20010918; ZA 200301778 A 20030304