EP 1322778 A4 20050615 - USE OF CYR61 IN THE TREATMENT AND DIAGNOSIS OF HUMAN UTERINE LEIOMYOMAS
Title (en)
USE OF CYR61 IN THE TREATMENT AND DIAGNOSIS OF HUMAN UTERINE LEIOMYOMAS
Title (de)
ANWENDUNG VON CYR61 IN DER BEHANDLUNG UND DIAGNOSE VON MENSCHLICHEN UTERUSMYOMENE
Title (fr)
UTILISATION DE CYR61 DANS LE TRAITEMENT ET LE DIAGNOSTIC DES LEIOMYOMES UTERINS CHEZ LA FEMME
Publication
Application
Priority
- US 0130783 W 20010928
- US 23688700 P 20000929
Abstract (en)
[origin: WO0226193A2] The present invention relates to methods of inhibiting uterine leiomyoma proliferation and preventing formation of uterine leiomyomas, compounds and compositions that stimulate induction of the <i>Cyr61</i> gene and compounds that increase Cyr61 activity. The present invention also relates to methods of screening ligands that regulate Cyr61 protein expression. The invention further relates to methods of diagnosing patients with uterine leiomyomas associated with a downregulation of Cyr61 expression. The invention also describes antibodies and related pharmaceutical compositions.
IPC 1-7
IPC 8 full level
A01K 67/027 (2006.01); A61K 31/7036 (2006.01); A61K 31/7088 (2006.01); A61K 38/00 (2006.01); A61K 38/18 (2006.01); A61K 38/22 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61K 49/00 (2006.01); A61P 15/00 (2006.01); A61P 35/00 (2006.01); C07K 16/18 (2006.01); C07K 16/22 (2006.01); C07K 16/46 (2006.01); C12N 15/09 (2006.01); C12P 21/08 (2006.01); C12Q 1/02 (2006.01); C12Q 1/68 (2006.01); G01N 33/15 (2006.01); G01N 33/50 (2006.01); G01N 33/68 (2006.01)
CPC (source: EP)
A61K 38/18 (2013.01); A61K 49/0004 (2013.01); A61P 15/00 (2017.12); A61P 35/00 (2017.12); C07K 16/18 (2013.01); C07K 16/22 (2013.01); G01N 33/5011 (2013.01); G01N 33/57442 (2013.01); A61K 48/00 (2013.01); A61K 2039/505 (2013.01)
Citation (search report)
- No further relevant documents disclosed
- See references of WO 0226193A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0226193 A2 20020404; WO 0226193 A3 20021003; WO 0226193 A9 20030220; AU 9647701 A 20020408; CA 2423413 A1 20020404; EP 1322778 A2 20030702; EP 1322778 A4 20050615; JP 2004509909 A 20040402
DOCDB simple family (application)
US 0130783 W 20010928; AU 9647701 A 20010928; CA 2423413 A 20010928; EP 01977351 A 20010928; JP 2002530024 A 20010928