Global Patent Index - EP 1322778 A4

EP 1322778 A4 20050615 - USE OF CYR61 IN THE TREATMENT AND DIAGNOSIS OF HUMAN UTERINE LEIOMYOMAS

Title (en)

USE OF CYR61 IN THE TREATMENT AND DIAGNOSIS OF HUMAN UTERINE LEIOMYOMAS

Title (de)

ANWENDUNG VON CYR61 IN DER BEHANDLUNG UND DIAGNOSE VON MENSCHLICHEN UTERUSMYOMENE

Title (fr)

UTILISATION DE CYR61 DANS LE TRAITEMENT ET LE DIAGNOSTIC DES LEIOMYOMES UTERINS CHEZ LA FEMME

Publication

EP 1322778 A4 20050615 (EN)

Application

EP 01977351 A 20010928

Priority

  • US 0130783 W 20010928
  • US 23688700 P 20000929

Abstract (en)

[origin: WO0226193A2] The present invention relates to methods of inhibiting uterine leiomyoma proliferation and preventing formation of uterine leiomyomas, compounds and compositions that stimulate induction of the <i>Cyr61</i> gene and compounds that increase Cyr61 activity. The present invention also relates to methods of screening ligands that regulate Cyr61 protein expression. The invention further relates to methods of diagnosing patients with uterine leiomyomas associated with a downregulation of Cyr61 expression. The invention also describes antibodies and related pharmaceutical compositions.

IPC 1-7

C12P 19/34; A61K 38/00; A61K 48/00

IPC 8 full level

A01K 67/027 (2006.01); A61K 31/7036 (2006.01); A61K 31/7088 (2006.01); A61K 38/00 (2006.01); A61K 38/18 (2006.01); A61K 38/22 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61K 49/00 (2006.01); A61P 15/00 (2006.01); A61P 35/00 (2006.01); C07K 16/18 (2006.01); C07K 16/22 (2006.01); C07K 16/46 (2006.01); C12N 15/09 (2006.01); C12P 21/08 (2006.01); C12Q 1/02 (2006.01); C12Q 1/68 (2006.01); G01N 33/15 (2006.01); G01N 33/50 (2006.01); G01N 33/68 (2006.01)

CPC (source: EP)

A61K 38/18 (2013.01); A61K 49/0004 (2013.01); A61P 15/00 (2017.12); A61P 35/00 (2017.12); C07K 16/18 (2013.01); C07K 16/22 (2013.01); G01N 33/5011 (2013.01); G01N 33/57442 (2013.01); A61K 48/00 (2013.01); A61K 2039/505 (2013.01)

Citation (search report)

  • No further relevant documents disclosed
  • See references of WO 0226193A2

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

DOCDB simple family (publication)

WO 0226193 A2 20020404; WO 0226193 A3 20021003; WO 0226193 A9 20030220; AU 9647701 A 20020408; CA 2423413 A1 20020404; EP 1322778 A2 20030702; EP 1322778 A4 20050615; JP 2004509909 A 20040402

DOCDB simple family (application)

US 0130783 W 20010928; AU 9647701 A 20010928; CA 2423413 A 20010928; EP 01977351 A 20010928; JP 2002530024 A 20010928