Global Patent Index - EP 1323827 A3

EP 1323827 A3 20031217 - Method for producing optically active 2-hydroxycycloalkanecarboxylic acid ester

Title (en)

Method for producing optically active 2-hydroxycycloalkanecarboxylic acid ester

Title (de)

Verfahren zur Herstellung von optisch aktiven 2-Hydroxy-Cycloalkancarbonsäure-Estern

Title (fr)

Procédé de préparation d'esters d'acide 2-hydroxy-cycloalkane carboxylique optiquement actifs

Publication

EP 1323827 A3 20031217 (EN)

Application

EP 02258814 A 20021220

Priority

  • JP 2001395885 A 20011227
  • JP 2001395884 A 20011227
  • JP 2002107648 A 20020410

Abstract (en)

[origin: EP1323827A2] There is disclosed a method for producing optically active 2-hydroxycycloalkanecarboxylic acid ester characterized by the steps of: allowing 2-oxocycloalkanecarboxylic acid ester to react with a transformant, or a dead cell or extract thereof, artificially provided with an ability to asymmetrically reduce 2-oxocycloalkanecarboxylic acid ester to optically active 2-hydroxycycloalkanccarboxylic acid ester and an ability to regenerate a coenzyme on which an enzyme having the former ability depends; and collecting the resulting optically active 2-hydroxycycloalkanecarboxylic acid ester.

IPC 1-7

C12P 7/62; C12P 7/42; C12N 1/21; C12N 15/53; C12N 15/70

IPC 8 full level

C12N 15/09 (2006.01); C12N 1/21 (2006.01); C12N 9/02 (2006.01); C12N 15/53 (2006.01); C12P 7/42 (2006.01); C12P 7/62 (2006.01)

CPC (source: EP US)

C12N 9/0008 (2013.01 - EP US); C12P 7/42 (2013.01 - EP US); C12P 7/62 (2013.01 - EP US)

Citation (search report)

  • [XY] EP 0501353 A2 19920902 - TAKEDA CHEMICAL INDUSTRIES LTD [JP]
  • [PA] EP 1213354 A2 20020612 - SUMITOMO CHEMICAL CO [JP]
  • [A] ITOH N ET AL: "Purification and characterization of phenylacetaldehyde reductase from a styrene-assimilating Corynebacterium strain, ST-10", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, WASHINGTON,DC, US, vol. 63, no. 10, October 1997 (1997-10-01), pages 3783 - 3788, XP002221910, ISSN: 0099-2240
  • [A] WANG J-C ET AL: "Cloning, sequence analysis, and expression in Escherichia coli of the gene encoding phenylacetaldehyde reductase from styrene-assimilating Corynebacterium sp. strain ST-10", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, SPRINGER VERLAG, BERLIN, DE, vol. 52, no. 3, 1999, pages 386 - 392, XP002221908, ISSN: 0175-7598
  • [A] ITOH N ET AL: "Production of chiral alcohols by enantioselective reduction with NADH-dependent phenylacetaldehyde reductase from Corynebacterium strain, ST-10", JOURNAL OF MOLECULAR CATALYSIS. B, ENZYMATIC, ELSEVIER, AMSTERDAM,, NL, vol. 6, no. 1-2, 4 January 1999 (1999-01-04), pages 41 - 50, XP002221909, ISSN: 1381-1177
  • [A] NAKAMURA K ET AL: "Recent developments in asymmetric reduction of ketones with biocatalysts", TETRAHEDRON: ASYMMETRY, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 14, no. 18, 19 September 2003 (2003-09-19), pages 2659 - 2681, XP004455733, ISSN: 0957-4166
  • [PY] ITOH N ET AL: "Chiral alcohol production by NADH-dependent phenylacetaldehyde reductase coupled with in situ regeneration of NADH", EUROPEAN JOURNAL OF BIOCHEMISTRY, BERLIN, DE, vol. 269, no. 9, May 2002 (2002-05-01), pages 2394 - 2402, XP002221911, ISSN: 0014-2956

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SI SK TR

DOCDB simple family (publication)

EP 1323827 A2 20030702; EP 1323827 A3 20031217; JP 2003250577 A 20030909; US 2003186400 A1 20031002

DOCDB simple family (application)

EP 02258814 A 20021220; JP 2002107648 A 20020410; US 32710802 A 20021224