EP 1328549 A1 20030723 - HUMAN PROSTATE SPECIFIC G-PROTEIN RECEPTOR HPRAJ70
Title (en)
HUMAN PROSTATE SPECIFIC G-PROTEIN RECEPTOR HPRAJ70
Title (de)
FÜR DIE HUMANE PROSTATA SPEZIFISCHER G-PROTEIN-REZEPTOR HPRAJ70
Title (fr)
RECEPTEUR HPRAJ70 DE LA PROTEINE G SPECIFIQUE DE LA PROSTATE HUMAINE
Publication
Application
Priority
- US 0130628 W 20011002
- US 23727500 P 20001003
Abstract (en)
[origin: WO0228899A1] The present invention relates to PSGR, a novel prostate specific gene with homology to a G-protein coupled receptor overexpressed in prostate cancer. More specifically, the invention relates to PSGR polynucleotides and the polypeptides encoded by these polynucleotides, and the use of PSGR polynucleotides and polypeptides for detecting disorders of the reproductive system, including disorders of the prostate, particularly the presence of cancer. This invention relates to PSGR polynucleotides and polypeptides as well as vectors, host cells, antibodies directed to PSGR polynucleotides and polypeptides and recombinant and synthetic methods for producing the same. Also provided are methods for diagnosing, treating, preventing and/or prognosing disorders related to the prostate, including cancer. The invention further relates to screening methods for identifying agonists and antagonists of PSGR polynucleotides and polypeptides of the invention and methods and/or compositions for inhibiting or enhancing the production and/or function of the PSGR polypeptides of the present invention.
IPC 1-7
C07K 14/705; C07K 14/71; C07K 14/72; A61K 38/16; A61K 39/395; C12N 5/10; C12N 15/12; C12N 15/63; C12N 15/64
IPC 8 full level
C07K 14/705 (2006.01); C07K 16/28 (2006.01); C12N 15/12 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01)
CPC (source: EP)
C07K 14/705 (2013.01); C07K 16/28 (2013.01); A61K 38/00 (2013.01); A61K 39/00 (2013.01); A61K 2039/505 (2013.01); C07K 2317/622 (2013.01)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0228899 A1 20020411; AU 9643301 A 20020415; CA 2422642 A1 20020411; EP 1328549 A1 20030723; EP 1328549 A4 20041006
DOCDB simple family (application)
US 0130628 W 20011002; AU 9643301 A 20011002; CA 2422642 A 20011002; EP 01977303 A 20011002