Global Patent Index - EP 1332134 A2

EP 1332134 A2 20030806 - INHIBITORS OF PRENYL-PROTEIN TRANSFERASE

Title (en)

INHIBITORS OF PRENYL-PROTEIN TRANSFERASE

Title (de)

INHIBITOREN VON PRENYLPROTEIN-TRANSFERASE

Title (fr)

INHIBITEURS DE LA PRENYL-PROTEINE TRANSFERASE

Publication

EP 1332134 A2 20030806 (EN)

Application

EP 01998114 A 20011019

Priority

  • US 0150527 W 20011019
  • US 24323600 P 20001025

Abstract (en)

[origin: WO02060868A2] The present invention is directed to spirocyclic compounds which inhibit prenyl-protein transferase and the prenylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting prenyl-protein transferase and the prenylation of the oncogene protein Ras.

IPC 1-7

C07D 225/04; A61K 31/415; A61P 27/00; A61P 31/00; A61P 35/00

IPC 8 full level

A61P 27/00 (2006.01); A61P 27/12 (2006.01); A61P 31/00 (2006.01); A61P 31/12 (2006.01); A61P 35/00 (2006.01); C07D 498/22 (2006.01)

CPC (source: EP)

A61P 27/00 (2017.12); A61P 27/12 (2017.12); A61P 31/00 (2017.12); A61P 31/12 (2017.12); A61P 35/00 (2017.12); C07D 498/22 (2013.01)

Citation (search report)

See references of WO 02060868A2

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

DOCDB simple family (publication)

WO 02060868 A2 20020808; WO 02060868 A3 20030103; CA 2426684 A1 20020808; EP 1332134 A2 20030806

DOCDB simple family (application)

US 0150527 W 20011019; CA 2426684 A 20011019; EP 01998114 A 20011019