EP 1332146 A2 20030806 - SPIRO-PYRIMIDINE-2,4,6-TRIONE METALLOPROTEINASE INHIBITORS
Title (en)
SPIRO-PYRIMIDINE-2,4,6-TRIONE METALLOPROTEINASE INHIBITORS
Title (de)
SPIROPYRIMIDIN-2,4,6-TRIONE ALS METALLOPROTEINASE INHIBITOREN
Title (fr)
INHIBITEURS DE METALLOPROTEINASE SPIRO-PYRIMIDINE-2,4,6-TRIONE
Publication
Application
Priority
- IB 0101986 W 20011023
- US 24338900 P 20001026
Abstract (en)
[origin: WO0234753A2] The present invention relates to 5-spiro-pyrimidine-2,4,6-trione metalloproteinase inhibitors of the formula wherein said "A" is a 5-7 membered heterocyclic ring as defined in the specification and to pharmaceutical compositions and methods of treating inflammation, cancer and othter disorders.
IPC 1-7
C07D 487/10; A61K 31/527; A61P 29/00; A61P 35/00; C07D 471/10
IPC 8 full level
A61K 31/527 (2006.01); A61K 35/00 (2006.01); A61P 1/02 (2006.01); A61P 1/04 (2006.01); A61P 1/16 (2006.01); A61P 3/00 (2006.01); A61P 3/10 (2006.01); A61P 9/00 (2006.01); A61P 9/10 (2006.01); A61P 9/14 (2006.01); A61P 11/00 (2006.01); A61P 11/06 (2006.01); A61P 13/12 (2006.01); A61P 15/00 (2006.01); A61P 15/04 (2006.01); A61P 15/06 (2006.01); A61P 15/08 (2006.01); A61P 15/16 (2006.01); A61P 15/18 (2006.01); A61P 17/00 (2006.01); A61P 17/02 (2006.01); A61P 17/04 (2006.01); A61P 17/06 (2006.01); A61P 17/16 (2006.01); A61P 19/02 (2006.01); A61P 19/04 (2006.01); A61P 19/06 (2006.01); A61P 19/08 (2006.01); A61P 19/10 (2006.01); A61P 21/04 (2006.01); A61P 25/00 (2006.01); A61P 25/02 (2006.01); A61P 25/04 (2006.01); A61P 25/06 (2006.01); A61P 25/14 (2006.01); A61P 25/16 (2006.01); A61P 25/22 (2006.01); A61P 25/24 (2006.01); A61P 25/28 (2006.01); A61P 27/02 (2006.01); A61P 27/06 (2006.01); A61P 29/00 (2006.01); A61P 31/00 (2006.01); A61P 31/04 (2006.01); A61P 31/10 (2006.01); A61P 31/12 (2006.01); A61P 31/18 (2006.01); A61P 33/06 (2006.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01); A61P 37/00 (2006.01); A61P 37/04 (2006.01); A61P 37/06 (2006.01); A61P 37/08 (2006.01); A61P 43/00 (2006.01); C07D 209/00 (2006.01); C07D 221/00 (2006.01); C07D 239/00 (2006.01); C07D 471/10 (2006.01); C07D 487/10 (2006.01)
IPC 8 main group level
CPC (source: EP KR)
A61P 1/02 (2018.01 - EP); A61P 1/04 (2018.01 - EP); A61P 1/16 (2018.01 - EP); A61P 3/00 (2018.01 - EP); A61P 3/10 (2018.01 - EP); A61P 9/00 (2018.01 - EP); A61P 9/10 (2018.01 - EP); A61P 9/14 (2018.01 - EP); A61P 11/00 (2018.01 - EP); A61P 11/06 (2018.01 - EP); A61P 13/12 (2018.01 - EP); A61P 15/00 (2018.01 - EP); A61P 15/04 (2018.01 - EP); A61P 15/06 (2018.01 - EP); A61P 15/08 (2018.01 - EP); A61P 15/16 (2018.01 - EP); A61P 15/18 (2018.01 - EP); A61P 17/00 (2018.01 - EP); A61P 17/02 (2018.01 - EP); A61P 17/04 (2018.01 - EP); A61P 17/06 (2018.01 - EP); A61P 17/16 (2018.01 - EP); A61P 19/02 (2018.01 - EP); A61P 19/04 (2018.01 - EP); A61P 19/06 (2018.01 - EP); A61P 19/08 (2018.01 - EP); A61P 19/10 (2018.01 - EP); A61P 21/04 (2018.01 - EP); A61P 25/00 (2018.01 - EP); A61P 25/02 (2018.01 - EP); A61P 25/04 (2018.01 - EP); A61P 25/06 (2018.01 - EP); A61P 25/14 (2018.01 - EP); A61P 25/16 (2018.01 - EP); A61P 25/22 (2018.01 - EP); A61P 25/24 (2018.01 - EP); A61P 25/28 (2018.01 - EP); A61P 27/02 (2018.01 - EP); A61P 27/06 (2018.01 - EP); A61P 29/00 (2018.01 - EP); A61P 31/00 (2018.01 - EP); A61P 31/04 (2018.01 - EP); A61P 31/10 (2018.01 - EP); A61P 31/12 (2018.01 - EP); A61P 31/18 (2018.01 - EP); A61P 33/06 (2018.01 - EP); A61P 35/00 (2018.01 - EP); A61P 35/02 (2018.01 - EP); A61P 37/00 (2018.01 - EP); A61P 37/04 (2018.01 - EP); A61P 37/06 (2018.01 - EP); A61P 37/08 (2018.01 - EP); A61P 43/00 (2018.01 - EP); C07D 471/10 (2013.01 - EP); C07D 487/10 (2013.01 - EP KR)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0234753 A2 20020502; WO 0234753 A3 20020815; AP 2001002318 A0 20011231; AR 035069 A1 20040414; AU 1081302 A 20020506; BG 107653 A 20031231; BR 0114913 A 20030701; CA 2425283 A1 20020502; CN 1501937 A 20040602; CZ 20031083 A3 20040317; EA 005762 B1 20050630; EA 200300306 A1 20030828; EC SP034567 A 20030625; EE 200300196 A 20031015; EP 1332146 A2 20030806; GT 200100213 A 20020703; HN 2001000244 A 20031107; HR P20030332 A2 20030630; HU P0301577 A2 20031128; HU P0301577 A3 20060228; IL 154948 A0 20031031; IS 6762 A 20030327; JP 2004518635 A 20040624; KR 20040004412 A 20040113; MA 26957 A1 20041220; MX PA03003735 A 20030728; NO 20031853 D0 20030424; NO 20031853 L 20030623; OA 12529 A 20060602; PA 8531401 A1 20030630; PE 20020589 A1 20020706; PL 366201 A1 20050124; SK 4972003 A3 20040504; SV 2003000705 A 20030113; TN SN01149 A1 20051110; ZA 200302190 B 20040428
DOCDB simple family (application)
IB 0101986 W 20011023; AP 2001002318 A 20011023; AR P010104977 A 20011024; AU 1081302 A 20011023; BG 10765303 A 20030320; BR 0114913 A 20011023; CA 2425283 A 20011023; CN 01817923 A 20011023; CZ 20031083 A 20011023; EA 200300306 A 20011023; EC SP034567 A 20030425; EE P200300196 A 20011023; EP 01978721 A 20011023; GT 200100213 A 20011025; HN 2001000244 A 20011024; HR P20030332 A 20030428; HU P0301577 A 20011023; IL 15494801 A 20011023; IS 6762 A 20030327; JP 2002537743 A 20011023; KR 20037005753 A 20030425; MA 27117 A 20030422; MX PA03003735 A 20011023; NO 20031853 A 20030424; OA 1200300123 A 20011023; PA 8531401 A 20011026; PE 2001001060 A 20011025; PL 36620101 A 20011023; SK 4972003 A 20011023; SV 2001000705 A 20011025; TN SN01149 A 20011025; ZA 200302190 A 20030319