EP 1333023 B1 20101222 - Immunogens, antibodies and conjugates to ketamine and its metabolites
Title (en)
Immunogens, antibodies and conjugates to ketamine and its metabolites
Title (de)
Immunogene, Antikörper und Konjugate für Ketamin und dessen Metaboliten
Title (fr)
Immunogènes, anticorps et conjugués pour la ketamine et ses métabolites
Publication
Application
Priority
- EP 03075218 A 20030123
- EP 02075445 A 20020131
Abstract (en)
[origin: EP1333023A1] The present invention discloses haptens derivatised with a crosslinker at the N-position of norketaminc or at an O- position of a hydroxynorketamine or of a hydroxyketamine. The invention also provides immunogens comprising such haptens, coupled to an antigenicity-conferring carrier material, as well as, antibodies raised against such haptens. In addition, the invention concerns conjugates comprising such haptens, covalently bonded to a detectable labelling agent. The invention also provides methods and kits for detecting or determining ketamine and its primary metabolite, norketamine, using conjugates and antibodies of the present invention. <IMAGE>
IPC 8 full level
C07K 16/44 (2006.01); A61K 47/48 (2006.01); C07C 229/14 (2006.01); C07C 327/22 (2006.01); G01N 33/94 (2006.01)
CPC (source: EP US)
A61K 47/64 (2017.07 - EP US); A61K 47/646 (2017.07 - EP US); C07K 16/44 (2013.01 - EP US); G01N 33/94 (2013.01 - EP US); Y10S 436/815 (2013.01 - EP US); Y10S 436/823 (2013.01 - EP US); Y10S 530/807 (2013.01 - EP US); Y10T 436/13 (2015.01 - EP US); Y10T 436/17 (2015.01 - EP US)
Citation (examination)
LAD S.S; DORNINOS E.F.: "Gas Chromatography Mass Spectrometry Assay for Ketamine and its Metabolites in Plasma", BIOMEDICAL MASS SPECTROMETRY, vol. 4, October 1977 (1977-10-01), pages 317 - 321
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT SE SI SK TR
DOCDB simple family (publication)
EP 1333023 A1 20030806; EP 1333023 B1 20101222; AT E492565 T1 20110115; CN 100519513 C 20090729; CN 1496974 A 20040519; DE 60335428 D1 20110203; ES 2358737 T3 20110513; US 2003224447 A1 20031204; US 7371829 B2 20080513
DOCDB simple family (application)
EP 03075218 A 20030123; AT 03075218 T 20030123; CN 03136682 A 20030131; DE 60335428 T 20030123; ES 03075218 T 20030123; US 35534803 A 20030131