EP 1333827 A2 20030813 - ESTROGEN RECEPTOR MODULATORS
Title (en)
ESTROGEN RECEPTOR MODULATORS
Title (de)
ÖSTROGENREZEPTOR-MODULATOREN
Title (fr)
MODULATEURS DE RECEPTEURS D'OESTROGENES
Publication
Application
Priority
- US 0142735 W 20011015
- US 24158200 P 20001019
Abstract (en)
[origin: WO0232377A2] The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for treatment or prevention of a variety of conditions related to estrogen functioning including: bone loss, bone fractures, osteoporosis, cartilage degeneration, endometriosis, uterine fibroid disease, hot flashes, increased levels of LDL cholesterol, cardiovascular disease, impairment of cognitive functioning, cerebral degenerative disorders, restinosis, gynacomastia, vascular smooth muscle cell proliferation, obesity, incontinence, and cancer, in particular of the breast, uterus and prostate.
IPC 1-7
A61K 31/395; A61K 31/55; A61K 31/445; A61K 31/40; A61P 5/00; C07D 405/00; C07D 409/00; C07D 205/00; C07D 213/02; C07D 411/00
IPC 8 full level
A61K 31/395 (2006.01); A61K 31/397 (2006.01); A61K 31/40 (2006.01); A61K 31/4025 (2006.01); A61K 31/445 (2006.01); A61K 31/4535 (2006.01); A61K 31/55 (2006.01); A61P 3/04 (2006.01); A61P 3/06 (2006.01); A61P 5/00 (2006.01); A61P 5/30 (2006.01); A61P 5/32 (2006.01); A61P 9/00 (2006.01); A61P 9/10 (2006.01); A61P 15/00 (2006.01); A61P 19/00 (2006.01); A61P 19/10 (2006.01); A61P 25/28 (2006.01); A61P 35/00 (2006.01); A61P 35/04 (2006.01); C07D 205/00 (2006.01); C07D 213/02 (2006.01); C07D 327/06 (2006.01); C07D 339/08 (2006.01); C07D 405/00 (2006.01); C07D 409/00 (2006.01); C07D 411/00 (2006.01); C07D 411/04 (2006.01); C07D 411/12 (2006.01)
CPC (source: EP KR)
A61P 3/04 (2018.01 - EP); A61P 3/06 (2018.01 - EP); A61P 5/00 (2018.01 - EP); A61P 5/30 (2018.01 - EP); A61P 5/32 (2018.01 - EP); A61P 9/00 (2018.01 - EP); A61P 9/10 (2018.01 - EP); A61P 15/00 (2018.01 - EP); A61P 19/00 (2018.01 - EP); A61P 19/10 (2018.01 - EP); A61P 25/28 (2018.01 - EP); A61P 35/00 (2018.01 - EP); A61P 35/04 (2018.01 - EP); C07D 327/06 (2013.01 - EP); C07D 339/08 (2013.01 - EP); C07D 411/04 (2013.01 - EP); C07D 411/12 (2013.01 - KR)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0232377 A2 20020425; WO 0232377 A3 20020822; AU 2002232381 B2 20041118; AU 3238102 A 20020429; BG 107676 A 20031128; BR 0114689 A 20030701; CA 2424729 A1 20020425; CN 1469743 A 20040121; EA 200300474 A1 20031030; EC SP034558 A 20030625; EE 200300153 A 20030616; EP 1333827 A2 20030813; HU P0303563 A2 20040301; IL 154984 A0 20031031; IS 6761 A 20030327; JP 2004511502 A 20040415; KR 20030042020 A 20030527; MX PA03003485 A 20030714; NO 20031737 D0 20030415; NO 20031737 L 20030619; PE 20021083 A1 20021216; PL 361053 A1 20040920; SK 4772003 A3 20030805
DOCDB simple family (application)
US 0142735 W 20011015; AU 2002232381 A 20011015; AU 3238102 A 20011015; BG 10767603 A 20030326; BR 0114689 A 20011015; CA 2424729 A 20011015; CN 01817672 A 20011015; EA 200300474 A 20011015; EC SP034558 A 20030417; EE P200300153 A 20011015; EP 01987654 A 20011015; HU P0303563 A 20011015; IL 15498401 A 20011015; IS 6761 A 20030327; JP 2002535616 A 20011015; KR 20037005518 A 20030419; MX PA03003485 A 20011015; NO 20031737 A 20030415; PE 2002000308 A 20020415; PL 36105301 A 20011015; SK 4772003 A 20011015