Global Patent Index - EP 1334127 A1

EP 1334127 A1 20030813 - SINGLE-CHAIN MULTIMERIC POLYPEPTIDES

Title (en)

SINGLE-CHAIN MULTIMERIC POLYPEPTIDES

Title (de)

EINZELKETTE MULTIMERE POLYPEPTIDE

Title (fr)

POLYPEPTIDES MULTIMERES COMPORTANT UNE SEULE CHAINE

Publication

EP 1334127 A1 20030813 (EN)

Application

EP 01980207 A 20011101

Priority

  • DK 0100724 W 20011101
  • DK PA200001647 A 20001102

Abstract (en)

[origin: WO0236626A1] The invention relates to single-chain multimeric polypeptides comprising at least two units of a monomeric polypeptide linked via a peptide bond or a peptide linker, wherein the monomeric polypeptide is of a type that is biologically active in monomeric form, and to polypeptide conjugates having at least one non-polypeptide moiety covalently bound to an attachment group of the polypeptide. The polypeptide is preferably a G-CSF dimer bound to a polymer molecule, preferably to one or more polyethylene glycol molecules.

IPC 1-7

C07K 14/535; A61K 47/48; C07K 14/52; C12N 15/63; A61P 7/00; A61K 38/19

IPC 8 full level

A61K 47/48 (2006.01); A61P 7/00 (2006.01); C07K 14/535 (2006.01); A61K 38/00 (2006.01)

CPC (source: EP)

A61K 47/60 (2017.07); A61P 7/00 (2017.12); C07K 14/535 (2013.01); A61K 38/00 (2013.01); C07K 2319/00 (2013.01)

Citation (search report)

See references of WO 0236626A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

DOCDB simple family (publication)

WO 0236626 A1 20020510; AU 1210802 A 20020515; EP 1334127 A1 20030813

DOCDB simple family (application)

DK 0100724 W 20011101; AU 1210802 A 20011101; EP 01980207 A 20011101