Global Patent Index - EP 1334128 A2

EP 1334128 A2 20030813 - NEW MULTIMERIC INTERFERON BETA POLYPEPTIDES

Title (en)

NEW MULTIMERIC INTERFERON BETA POLYPEPTIDES

Title (de)

NEUE MULTIMERE INTERFERON-BETA-POLYPEPTIDE

Title (fr)

NOUVEAUX POLYPEPTIDES $G(B) INTERFERON MULTIMERES

Publication

EP 1334128 A2 20030813 (EN)

Application

EP 01980206 A 20011101

Priority

  • DK 0100723 W 20011101
  • DK PA200001646 A 20001102

Abstract (en)

[origin: WO0236628A2] The present invention relates to a single chain multimeric interferon b polypeptide comprising at least two monomers linked via a peptide bond or a peptide linker, wherein at least one of said monomers is an interferon beta monomer comprising an amino acid sequence that differs from that of wildtype human interferon beta in at least one introduced glycosylation site, methods of preparing such polypeptides or conjugates, and the use of such polypeptides in therapy, in particular for the treatment of multiple sclerosis.

IPC 1-7

C07K 14/565; A61K 38/21

IPC 8 full level

A61K 38/21 (2006.01); A61K 47/48 (2006.01); C07K 14/565 (2006.01); A61K 38/00 (2006.01)

CPC (source: EP)

A61K 38/215 (2013.01); A61K 47/65 (2017.07); C07K 14/565 (2013.01); C07K 2319/00 (2013.01)

Citation (search report)

See references of WO 0236628A2

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

DOCDB simple family (publication)

WO 0236628 A2 20020510; WO 0236628 A3 20030103; AU 1210702 A 20020515; EP 1334128 A2 20030813

DOCDB simple family (application)

DK 0100723 W 20011101; AU 1210702 A 20011101; EP 01980206 A 20011101