EP 1334356 A4 20041006 - METHOD FOR GENERATING CLONED ANIMALS USING CHROMOSOME SHUFFLING
Title (en)
METHOD FOR GENERATING CLONED ANIMALS USING CHROMOSOME SHUFFLING
Title (de)
VERFAHREN ZUR ERZEUGUNG KLONIERTER TIERE UNTER VERWENDUNG VON CHROMOSOMEN-SHUFFLING
Title (fr)
PROCEDE POUR CREER DES ANIMAUX CLONES PAR REARRANGEMENT CHROMOSOMIQUE
Publication
Application
Priority
- US 0131216 W 20011005
- US 23801400 P 20001006
Abstract (en)
[origin: WO0229002A2] The present invention concerns the use of chromosomal replacement techniques in the context of producing cloned and transgenic animals, in order to correct chromosome abnormalities or alter autosomal genotypes, and provide for novel breeding pairs by replacing the sex chromosome in animals to be cloned. Replacement of a sex chromosome, or an X or Y chromosome, will result in animals that are autosomally isogenic and sexually non-isogenic (AISN), with "autosomally isogenic" meaning that the paired sets of autosomes (non-sex chromosomes) in each animal are isogenic or identical. Also included in the invention are animals that are both "autosomally" and "allelically" isogenic whereby each particular pair of chromosomes is internally isogenic or identical within a single animal as well as between animals. Such animals are particularly useful in generating a line of cloned mammals using sexual reproduction, without having the undergo nuclear transfer in order to propagate cloned animals.
IPC 1-7
IPC 8 full level
A01K 67/027 (2006.01); C12N 15/85 (2006.01); C12N 15/87 (2006.01); C12N 15/877 (2010.01)
CPC (source: EP)
A01K 67/0273 (2013.01); C12N 15/8509 (2013.01); C12N 15/877 (2013.01); A01K 2217/05 (2013.01); A01K 2227/10 (2013.01); A01K 2227/101 (2013.01); A01K 2227/30 (2013.01); A01K 2227/40 (2013.01); A01K 2267/02 (2013.01); A01K 2267/025 (2013.01)
Citation (search report)
- [E] WO 02077175 A2 20021003 - ADVANCED CELL TECH INC [US], et al
- [DA] US 5240840 A 19930831 - FEINBERG ANDREW P [US], et al
- [A] WO 0042174 A1 20000720 - PPL THERAPEUTICS SCOTLAND LTD [GB], et al
- [A] WO 9937143 A2 19990729 - UNIV HAWAII [US]
- [PA] "CAN CLONING SAVE ENDANGERED SPECIES?", CURRENT BIOLOGY, CURRENT SCIENCE,, GB, vol. 11, no. 7, 2000, pages R245 - R246, XP002909800, ISSN: 0960-9822
- [A] BOURHIS LE D ET AL: "NUCLEAR TRANSFER FROM SEXED PARENT EMBRYOS IN CATTLE: EFFICIENCY AND BIRTH OF OFFSPRING", JOURNAL OF REPRODUCTION AND FERTILITY, JOURNALS OF REPRODUCTION AND FERTILITY LTD, GB, vol. 113, no. 2, July 1998 (1998-07-01), pages 343 - 348, XP000922632, ISSN: 0022-4251
- [A] WOLF E ET AL: "Nuclear transfer in mammals: Recent developments and future perspectives", JOURNAL OF BIOTECHNOLOGY, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 65, no. 2-3, 27 October 1998 (1998-10-27), pages 99 - 110, XP004144916, ISSN: 0168-1656
- [A] WHITE K L ET AL: "ESTABLISHMENT OF PREGNANCY AFTER THE TRANSFER OF NUCLEAR TRANSFER EMBRYOS PRODUCED FROM THE FUSION OF ARGALI (OVIS AMMON) NUCLEI INTO DOMESTIC SHEEP (OVIS ARIES) ENUCLEATED OOCYTES", CLONING, MARY ANN LIEBERT, NEW YORK, NY, US, vol. 1, no. 1, 1999, pages 47 - 54, XP002909799, ISSN: 0737-1454
- See references of WO 0229002A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0229002 A2 20020411; WO 0229002 A3 20020919; AU 1303302 A 20020415; CA 2425100 A1 20020411; EP 1334356 A2 20030813; EP 1334356 A4 20041006
DOCDB simple family (application)
US 0131216 W 20011005; AU 1303302 A 20011005; CA 2425100 A 20011005; EP 01981389 A 20011005