EP 1334358 A1 20030813 - TARGETING CELLS HAVING MAD2 MUTATION FOR TREATMENT AND/OR PREVENTION OF DISEASE
Title (en)
TARGETING CELLS HAVING MAD2 MUTATION FOR TREATMENT AND/OR PREVENTION OF DISEASE
Title (de)
BEHANDLUNG UND/ODER PROFYLAXE VON ERKRANKUNGEN DURCH ZELLEN MIT MAD2-MUTATION
Title (fr)
CIBLAGE DE CELLULES A MUTATION MAD2 POUR LE TRAITEMENT OU LA PREVENTION DE MALADIE
Publication
Application
Priority
US 0027462 W 20001003
Abstract (en)
[origin: WO03044525A1] The present invention relates to composition and methods of identifying one or more secondary drug targets and their use in the identification of drugs or drug candidates, particularly for the treatment of cancer or cell replication disorders. The yeast-based synthetic lethal screens are used to functionally identify and validate new gene targets to kill cells with defects in cell cycle pathways. These newly identified gene targets can be used to develop new therapeutics to treat cancer, benign cell growth, and yeast infections.
IPC 1-7
IPC 8 full level
A61K 31/7088 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61P 9/10 (2006.01); A61P 13/12 (2006.01); A61P 17/00 (2006.01); A61P 17/02 (2006.01); A61P 17/06 (2006.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01); A61P 37/04 (2006.01); A61P 43/00 (2006.01); C12M 1/34 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12Q 1/02 (2006.01); C12Q 1/68 (2006.01); C12Q 1/6886 (2018.01); G01N 33/15 (2006.01); G01N 33/50 (2006.01)
CPC (source: EP)
A61P 9/10 (2017.12); A61P 13/12 (2017.12); A61P 17/00 (2017.12); A61P 17/02 (2017.12); A61P 17/06 (2017.12); A61P 35/00 (2017.12); A61P 35/02 (2017.12); A61P 37/04 (2017.12); A61P 43/00 (2017.12); C12Q 1/6886 (2013.01); G01N 33/5011 (2013.01); C12Q 2600/136 (2013.01)
Citation (search report)
See references of WO 03044525A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 03044525 A1 20030530; AU 2000280405 A1 20030610; AU 7859700 A 20030610; EP 1334358 A1 20030813; JP 2005509447 A 20050414
DOCDB simple family (application)
US 0027462 W 20001003; AU 2000280405 A 20001003; AU 7859700 A 20001003; EP 00968724 A 20001003; JP 2003546104 A 20001003