EP 1335746 A2 20030820 - RECOMBINED ANTI-GPIIB/IIIA ANTIBODIES USED FOR INHIBITING ANGIOGENESIS
Title (en)
RECOMBINED ANTI-GPIIB/IIIA ANTIBODIES USED FOR INHIBITING ANGIOGENESIS
Title (de)
REKOMBINANTE ANTI-GPIIB/IIIA-ANTIKÖRPER ALS MITTEL ZUR HEMMUNG DER ANGIOGENESE
Title (fr)
ANTICORPS RECOMBINANTS ANTI-GPIIB/IIIA UTILISES POUR INHIBER L'ANGIOGENESE
Publication
Application
Priority
- DE 10057443 A 20001120
- EP 0113445 W 20011120
Abstract (en)
[origin: WO0240048A2] The invention relates to the use of special antibodies optimised by phage-display of optimised antibodies against GPIIb/IIIa for combined inhibition of fibrinogen to platelets and the vitronectin binding to endothelial cells for therapy and/or prophylaxis of vascular clusion. The invention also relates to the use of said antibodies for inhibiting angiogenesis or/and for inhibiting the metastasis of tumours or/and for inhibiting intimal hyperplasia following vascular damage.
IPC 1-7
IPC 8 full level
A61K 48/00 (2006.01); A61K 39/395 (2006.01); A61P 7/02 (2006.01); A61P 9/00 (2006.01); A61P 9/10 (2006.01); A61P 35/04 (2006.01); A61P 43/00 (2006.01); C07K 16/28 (2006.01)
CPC (source: EP US)
A61P 7/02 (2017.12 - EP); A61P 9/00 (2017.12 - EP); A61P 9/10 (2017.12 - EP); A61P 35/04 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07K 16/2848 (2013.01 - EP US); A61K 2039/505 (2013.01 - EP US); C07K 2317/50 (2013.01 - EP US); C07K 2317/565 (2013.01 - EP US)
Citation (search report)
See references of WO 0240048A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0240048 A2 20020523; WO 0240048 A3 20020801; AU 2634202 A 20020527; CA 2428649 A1 20030513; DE 10057443 A1 20020523; EP 1335746 A2 20030820; JP 2004513927 A 20040513; US 2004022791 A1 20040205
DOCDB simple family (application)
EP 0113445 W 20011120; AU 2634202 A 20011120; CA 2428649 A 20011120; DE 10057443 A 20001120; EP 01995645 A 20011120; JP 2002542420 A 20011120; US 39970103 A 20030421