Global Patent Index - EP 1337657 A2

EP 1337657 A2 20030827 - HETEROLOGOUS EXPRESSION OF TAXANES

Title (en)

HETEROLOGOUS EXPRESSION OF TAXANES

Title (de)

HETEROLOGE EXPRESSION VON TAXANEN

Title (fr)

EXPRESSION HETEROLOGUE DES TAXANES

Publication

EP 1337657 A2 20030827 (EN)

Application

EP 01996617 A 20011116

Priority

  • DK 0100763 W 20011116
  • DK PA200001730 A 20001117
  • US 25384300 P 20001129

Abstract (en)

[origin: WO0240694A2] The present invention relates to a method of heterologous production of a taxane or a related compound by cloning a DNA sequence comprising a taxane synthesis pathway, making a DNA construct wherein said DNA sequence is under control of regulatory elements, introducing said DNA construct into a host cell, growing said host cell under conditions conductive to the production of the taxane in question, and recovering the taxane in question from the culture medium.The invention also relates to the DNA sequence comprising the taxane synthesis pathway, an expression vector comprising the taxane synthesis pathway, and a host cell comprising the expression vector comprising the taxane synthesis pathway being capable of heterologous expression of taxane.

IPC 1-7

C12P 17/00; C12N 15/82; C12N 15/74

IPC 8 full level

C12N 15/52 (2006.01); C12P 17/02 (2006.01)

CPC (source: EP)

C12N 15/52 (2013.01); C12P 17/02 (2013.01)

Citation (search report)

See references of WO 0240694A2

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

DOCDB simple family (publication)

WO 0240694 A2 20020523; WO 0240694 A3 20021003; AU 2350402 A 20020527; EP 1337657 A2 20030827

DOCDB simple family (application)

DK 0100763 W 20011116; AU 2350402 A 20011116; EP 01996617 A 20011116