EP 1343498 A1 20030917 - NOVEL USES OF NON-PEPTIDE BOMBESIN RECEPTOR ANTAGONISTS FOR TREATING ANXIETY AND PANIC DISORDERS
Title (en)
NOVEL USES OF NON-PEPTIDE BOMBESIN RECEPTOR ANTAGONISTS FOR TREATING ANXIETY AND PANIC DISORDERS
Title (de)
NEUE VERWENDUNGEN VON NICHT-PEPTIDISCHE BOMBESIN ANTAGONISTEN ZUR BEHANDLUNG VON ANGST- UND PANIKSTÖRUNGEN
Title (fr)
NOUVELLES UTILISATIONS D'UN ANTAGONISTE DU RECEPTEUR NON PEPTIDIQUE DE LA BOMBESINE POUR TRAITER L'ANGOISSE ET LA LES TROUBLES PANIQUES
Publication
Application
Priority
GB 0004915 W 20001220
Abstract (en)
[origin: WO0249644A1] New uses have been found for compounds of formula (I) in which Ar, Ar>1<, R>1<, R>2<, R>3<, R>4<, R>5<, R>6<, R>7<, R>8<, R>9<, j, k, l, m and n are as defined in the description. These uses for the diagnosis, prevention, or treatment of anxiety, social phobia and panic disorders, pulmonary hypertension, lung repair and lung development disorders, prostate cancer, pancreatic cancer, hepatic porphyria, visceral pain, gastrointestinal secretory disturbances including duodenal ulcer and <i>Helicobacter pylori</i> infection and neuropathic pain. There is also disclosed a method for diagnosing or treating cancers using a radiolabelled compound of Formula (I), and also a method for treating cancers using a conjugate of a compound of Formula (I) with a cytotoxic agent.
[origin: WO0249644A1] New uses have been found for compounds of formula (I) in which Ar, Ar1, R1, R2, R3, R4, R5, R6, R7, R8, R9, j, k, l, m and n are as defined in the description. These uses for the diagnosis, prevention, or treatment of anxiety, social phobia and panic disorders, pulmonary hypertension, lung repair and lung development disorders, prostate cancer, pancreatic cancer, hepatic porphyria, visceral pain, gastrointestinal secretory disturbances including duodenal ulcer and <i>Helicobacter pylori</i> infection and neuropathic pain. There is also disclosed a method for diagnosing or treating cancers using a radiolabelled compound of Formula (I), and also a method for treating cancers using a conjugate of a compound of Formula (I) with a cytotoxic agent.
IPC 1-7
A61K 31/4164; A61K 31/44; A61K 31/404; A61P 25/22; A61P 25/24
IPC 8 full level
A61K 31/404 (2006.01); A61K 31/4164 (2006.01); A61K 31/44 (2006.01); A61K 31/4439 (2006.01); A61K 51/04 (2006.01); A61P 25/22 (2006.01); A61P 25/24 (2006.01)
CPC (source: EP KR)
A61K 31/404 (2013.01 - EP); A61K 31/4164 (2013.01 - EP); A61K 31/44 (2013.01 - EP KR); A61K 31/4439 (2013.01 - EP); A61K 51/0402 (2013.01 - EP); A61K 51/0406 (2013.01 - EP); A61K 51/0446 (2013.01 - EP); A61K 51/0455 (2013.01 - EP); A61K 51/0459 (2013.01 - EP); A61P 25/22 (2018.01 - EP); A61P 25/24 (2018.01 - EP)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0249644 A1 20020627; AU 2381601 A 20020701; BR 0017393 A 20040203; CA 2432066 A1 20020627; CN 1461217 A 20031210; EP 1343498 A1 20030917; HU P0302496 A2 20031229; IL 155773 A0 20031223; KR 20040007425 A 20040124; MX PA03005567 A 20031006; PL 362254 A1 20041018
DOCDB simple family (application)
GB 0004915 W 20001220; AU 2381601 A 20001220; BR 0017393 A 20001220; CA 2432066 A 20001220; CN 00820082 A 20001220; EP 00987567 A 20001220; HU P0302496 A 20001220; IL 15577300 A 20001220; KR 20037008211 A 20030619; MX PA03005567 A 20001220; PL 36225400 A 20001220