EP 1344057 A2 20030917 - ORGAN SYSTEM MICROARRAYS
Title (en)
ORGAN SYSTEM MICROARRAYS
Title (de)
ORGAN SYSTEM MICROARRAYS
Title (fr)
MICROECHANTILLONS DE SYSTEMES D'ORGANES
Publication
Application
Priority
- US 0151190 W 20011112
- US 71069700 A 20001110
Abstract (en)
[origin: WO02061424A2] Organ system microarrays are provided comprising a substrate including a plurality of locations. Each location comprises a scaffold for supporting the growth and/or proliferation of cells and at lest one cell type. The microarrays provide reagents for testing the biological effect of test compounds on the function of miniature organ systems. In a further aspect of the invention, the microarrays allow expression profiles of an individual or population of individuals to be determined and compared. The organ system microarrays can be used in parallel with small animal testing or in post-animal testing to further characterize lead compounds prior to entering clinical trials, thus creating a substantial cost saving through the early elimination of lead compounds not likely to work <u>in vivo</u>.
IPC 1-7
IPC 8 full level
C12N 5/071 (2010.01); G01N 33/50 (2006.01); A61K 35/12 (2015.01)
CPC (source: EP)
C12N 5/0685 (2013.01); C12N 5/0688 (2013.01); G01N 33/5008 (2013.01); G01N 33/5011 (2013.01); G01N 33/5088 (2013.01); A61K 35/12 (2013.01); C12N 2502/1347 (2013.01); C12N 2502/28 (2013.01); C12N 2503/02 (2013.01); C12N 2510/00 (2013.01); C12N 2533/40 (2013.01); G01N 2800/52 (2013.01)
Citation (search report)
See references of WO 02061424A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 02061424 A2 20020808; WO 02061424 A3 20030123; EP 1344057 A2 20030917
DOCDB simple family (application)
US 0151190 W 20011112; EP 01998129 A 20011112