EP 1345502 A1 20030924 - CREATINE/CITRIC ACID COMPOUND, METHOD FOR THE PRODUCTION OF THE SAME AND THE USE THEREOF
Title (en)
CREATINE/CITRIC ACID COMPOUND, METHOD FOR THE PRODUCTION OF THE SAME AND THE USE THEREOF
Title (de)
KREATIN/CITRONENSÄURE-VERBINDUNG, VERFAHREN ZU IHRER HERSTELLUNG UND VERWENDUNG
Title (fr)
COMPOSE ACIDE CITRIQUE/CREATINE, PROCEDE DE FABRICATION ET UTILISATION
Publication
Application
Priority
- DE 10065478 A 20001228
- EP 0113332 W 20011116
Abstract (en)
[origin: WO02052957A1] The invention relates to addition and/or co-ordination compounds consisting of creatine and citric acid in the ratio of >1.0 to 3.0: 1.0. Said compounds are characterised in that they have (KBr) bands in the IR spectrum, where nu = 3425 (+/- 5) cm<-1> (s), 1624 (+/- 5) cm<-1> (m-s) and 1247 (+/- 5) cm<-1> (m). Said compounds, which preferably contain no organic solvent and are present in a solid, pulverulent form are produced in particular by a method, according to which, a1) creatine, containing a maximum content of 20 wt. % water, is reacted with citric acid or its salts at temperatures between 0 and 70 DEG C, or a2) creatine and citric acid or its salts, containing a total water content of between 5 and 15 wt. %, are ground at temperatures between 0 and 70 DEG C, or a3) creatine is reacted with citric acid or its salts, in the presence of a solvent at temperatures between 0 and 70 DEG C. The corresponding solvent is then eliminated to a maximum residual content of 1.0 wt. %. The invention also relates to formulations that are suitable for use as food supplements, feed additives, dietetic agents, in functional foods, as neuroprotective agents, in addition to in the cosmetics industry etc.
IPC 1-7
IPC 8 full level
A23K 1/16 (2006.01); A23L 33/175 (2016.01); A61K 9/14 (2006.01); A61K 9/20 (2006.01); A61K 31/155 (2006.01); A61K 31/194 (2006.01); A61K 31/195 (2006.01); A61K 31/198 (2006.01); A61K 45/06 (2006.01); A61K 47/04 (2006.01); A61K 47/12 (2006.01); A61K 47/26 (2006.01); A61K 47/46 (2006.01); A61P 3/00 (2006.01); A61P 3/02 (2006.01); A61P 21/04 (2006.01); A61P 25/02 (2006.01); C07C 279/14 (2006.01)
CPC (source: EP US)
A23L 33/175 (2016.07 - EP US); A61K 31/195 (2013.01 - EP US); A61K 31/198 (2013.01 - EP US); A61P 3/00 (2017.12 - EP); A61P 3/02 (2017.12 - EP); A61P 21/04 (2017.12 - EP); A61P 25/02 (2017.12 - EP); C07C 279/14 (2013.01 - EP US); A23V 2002/00 (2013.01 - EP US)
Citation (search report)
See references of WO 02052957A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 02052957 A1 20020711; DE 10065478 C1 20020829; EP 1345502 A1 20030924; JP 2005500978 A 20050113; US 2004077719 A1 20040422
DOCDB simple family (application)
EP 0113332 W 20011116; DE 10065478 A 20001228; EP 01272630 A 20011116; JP 2002553921 A 20011116; US 46591703 A 20031031