Global Patent Index - EP 1346057 A2

EP 1346057 A2 20030924 - METHOD FOR PRODUCING HETEROLOGOUS PROTEINS IN A HOMOTHALLIC FUNGUS OF THE SORDARIACEAE FAMILY

Title (en)

METHOD FOR PRODUCING HETEROLOGOUS PROTEINS IN A HOMOTHALLIC FUNGUS OF THE SORDARIACEAE FAMILY

Title (de)

VERFAHREN ZUM HERSTELLEN VON HETEROLOGEN PROTEINEN IN EINEM HOMOTHALLISCHEN PILZ DER FAMILIE SORDARIACEAE

Title (fr)

PROCEDE DE FABRICATION DE PROTEINES HETEROLOGUES DANS UN CHAMPIGNON HOMOTHALLIQUE DE LA FAMILLE SORDARIACEAE

Publication

EP 1346057 A2 20030924 (DE)

Application

EP 01988083 A 20011228

Priority

  • DE 10065681 A 20001229
  • DE 10123857 A 20010516
  • EP 0115354 W 20011228

Abstract (en)

[origin: WO02053758A2] The invention relates to a method for producing a heterologous protein in a filamentous fungus and to suitable promoters therefor. The invention also relates to vectors and host cells and to a kit and the use thereof. The aim of the invention is to provide a method for producing a heterologous protein in a filamentous fungus, which allows the efficient production of heterologous proteins and in which a contamination of the created protein by vegetative spores is prevented. To achieve this, the invention discloses a method for producing a heterologous protein in a filamentous fungus, which comprises (a) the cultivation of a homothallic fungus of the Sordariaceae family, which contains an expression cassette with the following elements in a functional combination: a promoter that is active in the fungus of the Sordariaceae family; a heterologous gene and a terminator that is active in the fungus of the Sordariaceae family and (b) the harvesting of the created protein in a manner known per se.

IPC 1-7

C12N 15/80; C12P 21/00

IPC 8 full level

C12N 1/15 (2006.01); C12N 15/80 (2006.01); C12P 21/00 (2006.01)

CPC (source: EP US)

C12N 1/145 (2021.05 - EP US); C12N 15/80 (2013.01 - EP US); C12P 21/00 (2013.01 - EP US); C12R 2001/645 (2021.05 - EP US)

Citation (search report)

See references of WO 02053758A2

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

DOCDB simple family (publication)

WO 02053758 A2 20020711; WO 02053758 A3 20021205; AU 2002240882 A1 20020716; CA 2433430 A1 20020711; EP 1346057 A2 20030924; US 2004077047 A1 20040422

DOCDB simple family (application)

EP 0115354 W 20011228; AU 2002240882 A 20011228; CA 2433430 A 20011228; EP 01988083 A 20011228; US 45186603 A 20031007