EP 1349555 A1 20031008 - TREATMENT OF CANCER BY REDUCTION OF INTRACELLULAR ENERGY AND PYRIMIDINES
Title (en)
TREATMENT OF CANCER BY REDUCTION OF INTRACELLULAR ENERGY AND PYRIMIDINES
Title (de)
BEHANDLUNG VON KREBS DURCH REDUKTION INTRAZELLULÄRER ENERGIE UND VON PYRIMIDINEN
Title (fr)
TRAITEMENT DU CANCER PAR REDUCTION D'ENERGIE INTRACELLULAIRE ET A L'AIDE DE PYRIMIDINES
Publication
Application
Priority
- US 0146886 W 20011204
- US 25099300 P 20001204
Abstract (en)
[origin: WO0245720A1] This invention provides a method for treating a cancer subject comprising administering to the subject a combination of ATP-depleting agents at concentrations which deplete the ATP level to at least 15 % of normal in cancer cells, a pyrimidine antagonist, and an anticancer agent to which the treated cancer is sensitive. This invention also provides a composition comprising a combination of ATP-depleting agents at concentrations which deplete the ATP level to at least 15 % of normal in cancer cells, a pyrimidine antagonist, and an anticancer agent to which the treated cancer is sensitive. Finally this invention provides a pharmaceutical composition comprising the above composition or a combination thereof and a pharmaceutically acceptable carrier.
IPC 1-7
IPC 8 full level
A61K 31/00 (2006.01); A61K 31/455 (2006.01); A61K 31/57 (2006.01); A61K 31/7072 (2006.01); A61K 31/7076 (2006.01); A61K 38/18 (2006.01); A61K 45/06 (2006.01)
CPC (source: EP)
A61K 31/00 (2013.01); A61K 31/455 (2013.01); A61K 31/57 (2013.01); A61K 31/7072 (2013.01); A61K 31/7076 (2013.01); A61K 45/06 (2013.01)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0245720 A1 20020613; AU 3656902 A 20020618; CA 2436847 A1 20020613; EP 1349555 A1 20031008; EP 1349555 A4 20070425
DOCDB simple family (application)
US 0146886 W 20011204; AU 3656902 A 20011204; CA 2436847 A 20011204; EP 01986104 A 20011204