EP 1349571 A2 20031008 - ROTAVIRUS ENTEROTOXIN NSP4 AND METHODS OF USING SAME
Title (en)
ROTAVIRUS ENTEROTOXIN NSP4 AND METHODS OF USING SAME
Title (de)
ROTAVIRUS-ENTEROTOXIN NSP4 UND VERFAHREN ZU SEINER VERWENDUNG
Title (fr)
ENTEROTOXINE NSP4 DE ROTAVIRUS ET SES METHODES D'UTILISATION
Publication
Application
Priority
- US 0145255 W 20011102
- US 70562100 A 20001103
Abstract (en)
[origin: WO0236172A2] The rotavirus non-structural glycoprotein, NSP4, performs multiple functions in the virus replication cycle, especially during viral morphogenesis. Specifically, NSP4 is an intracellular receptor that mediates the acquisition of a transient membrane envelope during the budding of newly formed subviral particles into the endoplasmic reticulum (ER). The present invention relates to NSP4 and methods of use. More particularly, it relates to the use of NSP4 and fragments thereof (NSP4 114-135, NSP4 120-147, NSP4 112-174, or NSP4 112-150) as a prevention and/or treatment of rotaviral disease.
IPC 1-7
IPC 8 full level
C07K 14/14 (2006.01)
CPC (source: EP)
C07K 14/005 (2013.01); A61K 2039/505 (2013.01); A61K 2039/522 (2013.01); A61K 2039/5256 (2013.01); A61K 2039/5258 (2013.01); C07K 2319/00 (2013.01); C12N 2710/14143 (2013.01); C12N 2720/12322 (2013.01)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0236172 A2 20020510; WO 0236172 A3 20020919; AU 2002502 A 20020515; CA 2427809 A1 20020510; EP 1349571 A2 20031008; EP 1349571 A4 20050216
DOCDB simple family (application)
US 0145255 W 20011102; AU 2002502 A 20011102; CA 2427809 A 20011102; EP 01992588 A 20011102