EP 1356075 A4 20050413 - PROTEIN SCAFFOLDS FOR ANTIBODY MIMICS AND OTHER BINDING PROTEINS
Title (en)
PROTEIN SCAFFOLDS FOR ANTIBODY MIMICS AND OTHER BINDING PROTEINS
Title (de)
PROTEINGERÜSTE FÜR ANTIKÖRPERMIMETIKA UND ANDERE BINDUNGSPROTEINE
Title (fr)
ECHAFAUDAGES PROTEINIQUES INTERNES POUR ANALOGUES D'ANTICORPS ET AUTRES PROTEINES DE LIAISON
Publication
Application
Priority
- US 0132233 W 20011016
- US 68856600 A 20001016
Abstract (en)
[origin: WO0232925A2] Disclosed herein are proteins that include an immunoglobulin fold and that can be used as scaffolds. Also disclosed herein are nucleic acids encoding such proteins and the use of such proteins in diagnostic methods and in methods for evolving novel compound-binding species and their ligands.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); C07K 14/00 (2006.01); C07K 14/47 (2006.01); C07K 14/525 (2006.01); C07K 14/715 (2006.01); C07K 14/76 (2006.01); C07K 16/00 (2006.01); C07K 16/18 (2006.01); C07K 16/24 (2006.01); C07K 17/00 (2006.01); C07K 19/00 (2006.01)
CPC (source: EP)
C07K 14/47 (2013.01); C07K 14/525 (2013.01); C07K 16/00 (2013.01); C07K 16/241 (2013.01); C07K 2317/22 (2013.01); C07K 2319/00 (2013.01)
Citation (search report)
- [X] WO 0034784 A1 20000615 - PHYLOS INC [US]
- [PX] WO 0164942 A1 20010907 - PHYLOS INC [US], et al
- [X] KOIDE A ET AL: "THE FIBRONECTIN TYPE III DOMAIN AS A SCAFFOLD FOR NOVEL BINDING PROTEINS", JOURNAL OF MOLECULAR BIOLOGY, LONDON, GB, vol. 284, 1998, pages 1141 - 1151, XP002944100, ISSN: 0022-2836
- [A] NYGREN PER-AKE ET AL: "Scaffolds for engineering novel binding sites in proteins", CURRENT OPINION IN STRUCTURAL BIOLOGY, CURRENT BIOLOGY LTD., LONDON, GB, vol. 7, no. 4, 1997, pages 463 - 469, XP002196760, ISSN: 0959-440X
- See references of WO 0232925A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0232925 A2 20020425; WO 0232925 A3 20030821; WO 0232925 A9 20030206; AU 1325102 A 20020429; AU 2002213251 B2 20070614; CA 2418835 A1 20020425; EP 1356075 A2 20031029; EP 1356075 A4 20050413; EP 2141243 A2 20100106; EP 2141243 A3 20100127; JP 2004526419 A 20040902; JP 2009183292 A 20090820; JP 2013162789 A 20130822; JP 2015051023 A 20150319; JP 5460097 B2 20140402; JP 5868346 B2 20160224
DOCDB simple family (application)
US 0132233 W 20011016; AU 1325102 A 20011016; AU 2002213251 A 20011016; CA 2418835 A 20011016; EP 01981621 A 20011016; EP 09167669 A 20011016; JP 2002536306 A 20011016; JP 2009078046 A 20090327; JP 2013084490 A 20130415; JP 2014252609 A 20141215