Title (en)

BACTERIAL ISOLATES FROM ORGANISMS THAT RESPIRE AT LEAST PARTIALLY THROUGH THEIR SKIN AND BIOLOGICALLY ACTIVE EXTRACTS DERIVED THEREFROM

Title (de)

BAKTERIENISOLATE VON ORGANISMEN, DIE ZUMINDEST TEILWEISE DURCH DIE HAUT ATMEN, UND DAVON ABGELEITETE, BIOLOGISCH WIRKSAME EXTRAKTE

Title (fr)

ISOLATS BACTERIENS A PARTIR D'ORGANISMES QUI RESPIRENT AU MOINS PAR LEUR PEAU ET EXTRAITS BIOLOGIQUEMENT ACTIFS DERIVES DE CEUX-CI.

Publication

EP 1357921 A2 20031105 (EN)

Application

EP 02714692 A 20020104

Priority

• US 0200217 W 20020104
• US 26002201 P 20010105

Abstract (en)

[origin: WO02078720A2] Extracts including a biologically active compound or combination of compounds derived from microorganisms isolated from mucus-producing organisms that respire at least partially through their skin. Rod-shaped bacteria isolated from the skin of salamanders and frogs are found to produce compound(s) which have antiviral, antitumor, antibacterial and antifungal properties. These compound(s) have an inhibitory effect on opportunistic human pathogens, including <i>Candida</i> sp., <i>Microsporum</i> sp., <i>Staphylococcus</i> sp., <i>Pseudomonas</i> sp., <i>Escherichia</i> sp.,and <i>Enterococcus</i> sp., as well as on HIV strains and tumor cell lines.

[origin: WO02078720A2] This invention discloses extracts including a biologically active compound or combination of compounds derived from microorganisms isolated from mucous-producing organisms that respire at least partially through their skin. Rod-shaped bacteria isolated from the skin of salamanders and frogs are found to produce compound(s) that have antiviral, antitumor, antibacterial and antifungal properties. These compounds have an inhibitory effect on opportunistic human pathogens, including Candida sp., Microsporum sp., Staphylococcus sp., Pseudomonas sp., Escherichia sp.,and Enterococcus sp., as well as on HIV strains and tumor cell lines.

IPC 1-7

A61K 35/00; A61K 38/43; C12P 1/00; C12P 39/00; G01N 33/567; G01N 33/569

IPC 8 full level

G01N 33/50 (2006.01); A61K 35/74 (2015.01); A61K 35/744 (2015.01); A61K 45/00 (2006.01); A61P 31/04 (2006.01); A61P 31/10 (2006.01); A61P 31/12 (2006.01); A61P 31/18 (2006.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01); A61P 37/04 (2006.01); C12P 1/04 (2006.01); C12Q 1/02 (2006.01); C12Q 1/04 (2006.01); C12Q 1/18 (2006.01); G01N 33/15 (2006.01); G01N 33/569 (2006.01)

CPC (source: EP)

A61K 35/74 (2013.01); A61K 35/744 (2013.01); A61P 31/04 (2017.12); A61P 31/10 (2017.12); A61P 31/12 (2017.12); A61P 31/18 (2017.12); A61P 35/00 (2017.12); A61P 35/02 (2017.12); A61P 37/04 (2017.12); C12N 1/205 (2021.05); C12P 1/04 (2013.01); C12Q 1/025 (2013.01); C12Q 1/04 (2013.01); C12Q 1/18 (2013.01); G01N 33/56911 (2013.01); G01N 33/56961 (2013.01); G01N 33/56988 (2013.01); C12R 2001/01 (2021.05); G01N 2333/005 (2013.01); G01N 2333/16 (2013.01); G01N 2333/21 (2013.01); G01N 2333/245 (2013.01); G01N 2333/265 (2013.01); G01N 2333/31 (2013.01); G01N 2333/315 (2013.01); G01N 2333/37 (2013.01); G01N 2333/38 (2013.01); G01N 2333/40 (2013.01); G01N 2333/4606 (2013.01); G01N 2500/20 (2013.01)

Citation (search report)

See references of WO 02078720A2

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

DOCDB simple family (publication)

WO 02078720 A2 20021010; WO 02078720 A3 20021205; AU 2002246943 A1 20021015; BR 0203466 A 20030311; CA 2433910 A1 20021010; CN 1455673 A 20031112; EP 1357921 A2 20031105; JP 2004521935 A 20040722

DOCDB simple family (application)

US 0200217 W 20020104; AU 2002246943 A 20020104; BR 0203466 A 20020104; CA 2433910 A 20020104; CN 02800047 A 20020104; EP 02714692 A 20020104; JP 2002576985 A 20020104