EP 1363942 A2 20031126 - POLYPEPTIDE FROM A HDM2 PROTEIN SPECIFIC MURINE ALPHA/BETA T-CELL RECEPTORS, NUCLEIC ACIDS CODING FOR THE ABOVE AND USE THEREOF
Title (en)
POLYPEPTIDE FROM A HDM2 PROTEIN SPECIFIC MURINE ALPHA/BETA T-CELL RECEPTORS, NUCLEIC ACIDS CODING FOR THE ABOVE AND USE THEREOF
Title (de)
POLYPEPTIDE EINES HDM2-PROTEIN SPEZIFISCHEN MURINEN ALPHA/BETA T-ZELL REZEPTORS, DIESE KODIERENDE NUKLEINSÜREN UND DEREN VERWENDUNG
Title (fr)
POLYPEPTIDES D'UN RECEPTEUR DE LYMPHOCYTES T ALPHA/BETA DES MURIDES SPECIFIQUE DE LA PROTEINE HDM2, ACIDES NUCLEIQUES LES CODANT ET LEUR UTILISATION
Publication
Application
Priority
- DE 10109854 A 20010301
- EP 0202187 W 20020228
Abstract (en)
[origin: WO02070552A2] The invention relates to polypeptides from a murine alpha / beta T-cell receptor, mediating a hdm2 protein-specific T-cell response, or functional variants or parts thereof, or nucleic acids coding for the above, functional variants, or parts thereof. The effect of the above is that hdm2 protein-expressing cells are recognised by t-cells provided with said genes, cytokines are expressed and a t-cell-induced lysis and/or apoptosis of tumour- or leukaemic-cells is induced.
[origin: WO02070552A2] The invention relates to polypeptides from a murine alpha / beta T-cell receptor, mediating a hdm2 protein-specific T-cell response, or functional variants or parts thereof, or nucleic acids coding for the above, functional variants, or parts thereof. The effect of the above is that hdm2 protein-expressing cells are recognised by t-cells provided with said genes, cytokines are expressed and a t-cell-induced lysis and/or apoptosis of tumour- or leukaemic-cells is induced.
IPC 1-7
IPC 8 full level
G01N 33/15 (2006.01); A61K 31/7088 (2006.01); A61K 35/26 (2006.01); A61K 38/00 (2006.01); A61K 39/395 (2006.01); A61K 48/00 (2006.01); C07K 14/705 (2006.01); C07K 14/725 (2006.01); C07K 16/28 (2006.01); C07K 19/00 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12P 21/08 (2006.01); C12Q 1/02 (2006.01)
CPC (source: EP)
A61P 35/00 (2017.12); C07K 14/7051 (2013.01)
Citation (search report)
See references of WO 02070552A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 02070552 A2 20020912; WO 02070552 A3 20021212; WO 02070552 A8 20021010; CA 2445013 A1 20020912; DE 10109854 A1 20020912; EP 1363942 A2 20031126; JP 2004535778 A 20041202
DOCDB simple family (application)
EP 0202187 W 20020228; CA 2445013 A 20020228; DE 10109854 A 20010301; EP 02722160 A 20020228; JP 2002569871 A 20020228