EP 1365761 A1 20031203 - THERAPEUTIC COMBINATION OF AMLODIPINE AND BENAZEPRIL
Title (en)
THERAPEUTIC COMBINATION OF AMLODIPINE AND BENAZEPRIL
Title (de)
THERAPEUTISCHE ZUSAMMENSETZUNG VON AMLODIPIN UND BENAZEPRIL
Title (fr)
COMBINAISON THERAPEUTIQUE D'AMLODIPINE ET DE BENAZEPRIL
Publication
Application
Priority
US 0034246 W 20001218
Abstract (en)
[origin: WO0249646A1] The present invention especially relates to the use of a combination comprising (1) an ACEI selected from the group consisting of benazepril, benazeprilat, and pharmaceuticall acceptable salts thereof, and (2) amlodipine or pharmaceutically acceptable salt thereof, for the manufacture a medicament for the treatment or prevention or delay of progression of a condition selected from the group consisting of hypertension, congestive heart failure, angina, myocardial infarction, artherosclerosis, diabetic nephropathy, diabetic cardiac myopathy, renal insufficiency, peripheral vascular disease, left ventricular hypertrophy, cognitive dysfunction, blood pressure-related cerebrovasular disease, stroke, pulmonary disease or pulmonary hypertension and headache; wherein (i) the amount of amlodipine or a pharmaceutically acceptable salt thereof corresponds to 6 about mg to 40 about mg of the free base and (ii) the amount of the ACE inhibitor or a pharmaceutically thereof corresponds to 20 about mg to 160 about mg of benazepril hydrochloride.
IPC 1-7
A61K 31/44; A61K 31/55; A61P 9/00; A61P 9/02; A61P 9/04; A61P 9/10; A61P 9/12; A61P 11/00; A61P 27/00; A61P 43/00
IPC 8 full level
C07D 223/16 (2006.01); A61K 9/48 (2006.01); A61K 31/44 (2006.01); A61K 31/4418 (2006.01); A61K 31/4422 (2006.01); A61K 31/55 (2006.01); A61K 45/06 (2006.01); A61K 47/04 (2006.01); A61K 47/12 (2006.01); A61K 47/26 (2006.01); A61K 47/32 (2006.01); A61K 47/36 (2006.01); A61K 47/38 (2006.01); A61P 3/10 (2006.01); A61P 9/00 (2006.01); A61P 9/02 (2006.01); A61P 9/04 (2006.01); A61P 9/10 (2006.01); A61P 9/12 (2006.01); A61P 11/00 (2006.01); A61P 13/12 (2006.01); A61P 25/00 (2006.01); A61P 25/04 (2006.01); A61P 25/06 (2006.01); A61P 25/28 (2006.01); A61P 27/00 (2006.01); A61P 43/00 (2006.01); C07D 211/90 (2006.01)
CPC (source: EP KR)
A61K 9/4808 (2013.01 - EP); A61K 31/44 (2013.01 - EP); A61K 31/55 (2013.01 - EP KR); A61K 45/06 (2013.01 - EP); A61P 1/00 (2017.12 - EP); A61P 3/10 (2017.12 - EP); A61P 9/00 (2017.12 - EP); A61P 9/02 (2017.12 - EP); A61P 9/04 (2017.12 - EP); A61P 9/06 (2017.12 - EP); A61P 9/10 (2017.12 - EP); A61P 9/12 (2017.12 - EP); A61P 11/00 (2017.12 - EP); A61P 13/12 (2017.12 - EP); A61P 25/00 (2017.12 - EP); A61P 25/04 (2017.12 - EP); A61P 25/06 (2017.12 - EP); A61P 25/28 (2017.12 - EP); A61P 27/00 (2017.12 - EP); A61P 43/00 (2017.12 - EP)
C-Set (source: EP)
Citation (search report)
See references of WO 0249645A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0249646 A1 20020627; AT E338549 T1 20060915; AU 2001225816 B2 20051013; AU 2002232620 B2 20051103; AU 2002232620 B9 20051124; AU 2581601 A 20020701; AU 3262002 A 20020701; BR 0017386 A 20040113; BR 0116228 A 20031230; CA 2432282 A1 20020627; CA 2432638 A1 20020627; CN 1461218 A 20031210; CN 1481241 A 20040310; CY 1106275 T1 20111012; CZ 20031677 A3 20031015; CZ 20031678 A3 20031015; CZ 301424 B6 20100224; DE 60122928 D1 20061019; DE 60122928 T2 20070906; DK 1345607 T3 20061227; EC SP034658 A 20030725; EP 1345607 A1 20030924; EP 1345607 B1 20060906; EP 1365761 A1 20031203; EP 1674099 A1 20060628; ES 2272565 T3 20070501; HK 1059566 A1 20040709; HU P0302455 A2 20031128; HU P0302455 A3 20050530; HU P0302456 A2 20031128; HU P0302456 A3 20040528; IL 156136 A0 20031223; IL 156267 A0 20040104; IL 190801 A0 20081103; IL 190802 A0 20081103; JP 2004516266 A 20040603; JP 2004519440 A 20040702; JP 2010043111 A 20100225; KR 20030061840 A 20030722; KR 20040007420 A 20040124; KR 20090033914 A 20090406; MX PA03005462 A 20030925; MX PA03005463 A 20030925; NO 20032765 D0 20030617; NO 20032765 L 20030814; NO 20032766 D0 20030617; NO 20032766 L 20030814; NZ 526467 A 20050429; PL 360989 A1 20040920; PL 362252 A1 20041018; PT 1345607 E 20070131; RU 2003121019 A 20050120; RU 2292206 C2 20070127; SI 1345607 T1 20070228; SK 7642003 A3 20031104; SK 7652003 A3 20031202; WO 0249645 A1 20020627; ZA 200304514 B 20040510
DOCDB simple family (application)
US 0148808 W 20011217; AT 01992150 T 20011217; AU 2001225816 A 20001218; AU 2002232620 A 20011217; AU 2581601 A 20001218; AU 3262002 A 20011217; BR 0017386 A 20001218; BR 0116228 A 20011217; CA 2432282 A 20011217; CA 2432638 A 20001218; CN 00820080 A 20001218; CN 01820839 A 20011217; CY 061101728 T 20061130; CZ 20031677 A 20011217; CZ 20031678 A 20001218; DE 60122928 T 20011217; DK 01992150 T 20011217; EC SP034658 A 20030617; EP 00989288 A 20001218; EP 01992150 A 20011217; EP 06003150 A 20011217; ES 01992150 T 20011217; HK 04100922 A 20040211; HU P0302455 A 20001218; HU P0302456 A 20011217; IL 15613600 A 20001218; IL 15626701 A 20011217; IL 19080108 A 20080410; IL 19080208 A 20080410; JP 2002550985 A 20001218; JP 2002550986 A 20011217; JP 2009235225 A 20091009; KR 20037007578 A 20030605; KR 20037007754 A 20030610; KR 20097004242 A 20090227; MX PA03005462 A 20001218; MX PA03005463 A 20011217; NO 20032765 A 20030617; NO 20032766 A 20030617; NZ 52646701 A 20011217; PL 36098901 A 20011217; PL 36225200 A 20001218; PT 01992150 T 20011217; RU 2003121019 A 20011217; SI 200130662 T 20011217; SK 7642003 A 20011217; SK 7652003 A 20001218; US 0034246 W 20001218; ZA 200304514 A 20030610