Global Patent Index - EP 1368368 A2

EP 1368368 A2 20031210 - COMPOSITIONS AND METHODS FOR BINDING AGGLOMERATION PROTEINS

Title (en)

COMPOSITIONS AND METHODS FOR BINDING AGGLOMERATION PROTEINS

Title (de)

ZUSAMMENSETZUNGEN UND VERFAHREN ZUR BINDUNG VON AGGLOMERATIONSPROTEINEN

Title (fr)

COMPOSITIONS ET METHODES DE LIAISON DE PROTEINES D'AGGLOMERATION

Publication

EP 1368368 A2 20031210 (EN)

Application

EP 02746458 A 20020530

Priority

  • US 0216922 W 20020530
  • US 29482201 P 20010531

Abstract (en)

[origin: WO02097049A2] Amplibody compositions and methods used to interact with agglomeration proteins are disclosed herein. Compositions herein comprise one or more DNA or RNA molecules having affinity for at least one agglomeration protein. The nucleic acid component is a naturally or non-naturally occuring molecule with twenty or more ribonucleotide bases. For RNA, at least one nucleotide sequence portion of this RNA molecule has affinity to at least one consensus sequence present in the agglomeration RNA-binding protein. The portion of nucleotide sequence of RNA having affinity for agglomeration proteins is a sequence that is derived from either and RNA virus, and RNA agglomeration proteins is a sequence that is derived from either and RNA virus, an RNA phage, a messenger RNA ("mRNA"), a ribosomal RNA ("rRNA), a transfer RNA ("tRNA"), a sequence that is received as a template by one or more RNA dependent RNA polymerases, or a combination thereof. Methods disclosed herein are directed towards detecting the presence of one or more agglomeration proteins in a sample matrix using the amplibody compositions described herein.

IPC 1-7

C07H 21/02

IPC 8 full level

C12N 15/09 (2006.01); C07H 21/02 (2006.01); C12Q 1/68 (2006.01); C12Q 1/70 (2006.01); G01N 33/68 (2006.01); C12Q 1/6834 (2018.01)

CPC (source: EP)

C12Q 1/702 (2013.01); G01N 33/6803 (2013.01); C12Q 1/6834 (2013.01)

C-Set (source: EP)

C12Q 1/702 + C12Q 2565/113 + C12Q 2525/161 + C12Q 2525/101

Citation (search report)

See references of WO 02097049A2

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

DOCDB simple family (publication)

WO 02097049 A2 20021205; WO 02097049 A3 20030925; AU 2002316178 A1 20021209; EP 1368368 A2 20031210; JP 2004520080 A 20040708

DOCDB simple family (application)

US 0216922 W 20020530; AU 2002316178 A 20020530; EP 02746458 A 20020530; JP 2003500218 A 20020530