EP 1368774 A2 20031210 - SYSTEM AND METHOD FOR MODELLING GENETIC, BIOCHEMICAL, BIOPHYSICAL AND ANATOMICAL INFORMATION
Title (en)
SYSTEM AND METHOD FOR MODELLING GENETIC, BIOCHEMICAL, BIOPHYSICAL AND ANATOMICAL INFORMATION
Title (de)
SYSTEM UND VERFAHREN ZUR MODELLIERUNG VON GENETISCHE, BIOCHEMISCHE, BIOPHYSISCHE UND ANATOMISCHE INFORMATION
Title (fr)
SYSTEME ET PROCEDE DE MODELISATION D'INFORMATIONS GENETIQUES, BIOCHIMIQUES, BIOPHYSIQUES ET ANATOMIQUES: IN SILICO CELL
Publication
Application
Priority
- US 0101988 W 20010122
- US 49957500 A 20000207
Abstract (en)
[origin: WO0157775A2] Genetic, biochemical, biophysical and anatomical information is integrated at the subcellular, cellular, tissue and organ level. At least one database containing biological information is used to generate at least one data structure having at least one attribute associated therewith. An interface interactively views, edits or links together attributes of the data structures to create at least one hierarchical description of subcellular, cellular, tissue and organ function. The hierarchical description may optionally be an elementary, binary or pathway data structure, or, alternatively, an anatomical data structure capable of being modified to form a structural model. A computational engine mathematically generates at least one data structure from the hierarchical description. Genetic information is accessed, tabulated and combined with functional information on the biochemical and physiological role of gene products. Computational models of genetic, biochemical and biophysical processes within cells and higher order systems are automatically formulated, solved and analyzed based on combination of genetic and functional information adduced. A dynamic tool is thereby provided for achieving discernible objectives, such as increased understanding of biological processes, identification of new drug targets for therapeutic intervention and predictions involving the outcome of drug screening. These objectives are accomplished by the realization of highly complex nonlinear dynamic interactions that occur between each gene or gene product.
IPC 1-7
IPC 8 full level
C12M 1/00 (2006.01); G16B 5/00 (2019.01); G06F 17/11 (2006.01); G06F 17/30 (2006.01); G06N 3/00 (2006.01); G16B 50/20 (2019.01)
IPC 8 main group level
G06F (2006.01)
CPC (source: EP US)
G16B 5/00 (2019.01 - EP US); G16B 50/20 (2019.01 - EP US); G16B 50/00 (2019.01 - EP); Y02A 90/10 (2017.12 - EP)
Citation (search report)
See references of WO 0157775A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0157775 A2 20010809; WO 0157775 A3 20031002; WO 0157775 A9 20031127; AU 3649001 A 20010814; CA 2399272 A1 20010809; EP 1368774 A2 20031210; IL 151070 A0 20030410; JP 2004501415 A 20040115
DOCDB simple family (application)
US 0101988 W 20010122; AU 3649001 A 20010122; CA 2399272 A 20010122; EP 01908645 A 20010122; IL 15107001 A 20010122; JP 2001556956 A 20010122