EP 1369415 A1 20031210 - Substituted pyrrolyl compounds for the treatment of inflammation
Title (en)
Substituted pyrrolyl compounds for the treatment of inflammation
Title (de)
Pyrrole Derivate zur Behandlung von Entzündungen
Title (fr)
Dérivés de pyrrole utilisés dans le traitement des inflammations
Publication
Application
Priority
- EP 97950891 A 19971209
- US 3268896 P 19961210
Abstract (en)
A class of pyrrolyl derivatives is described for use in treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by formula (I), wherein at least one of R<1> and R<2> is phenyl substituted with methylsulfonyl or aminosulfonyl. <CHEM>
IPC 1-7
C07D 207/333; A61K 31/40; C07D 401/04; C07D 207/33; C07D 207/337; C07D 207/36; C07D 207/34
IPC 8 full level
C07D 207/333 (2006.01); C07D 207/337 (2006.01); C07D 207/34 (2006.01); C07D 207/32 (2006.01)
CPC (source: EP)
C07D 207/333 (2013.01); C07D 207/337 (2013.01); C07D 207/34 (2013.01)
Citation (search report)
- [PX] EP 0799823 A1 19971008 - SANKYO CO [JP]
- [Y] DE 1938904 A1 19700205 - INNOTHERA LAB SA [FR]
- [YD] US 3427305 A 19690211 - CHINN LELAND J
- [PX] KHANNA ET AL.: "1,2-Diarylpyrroles as potent and selective inhibitors of cyclooxygenase-2", JOURNAL OF MEDICINAL CHEMISTRY, vol. 40, no. 11, 1997, pages 1619 - 33, XP002059990
- [YD] WILKERSON W W ET AL: "ANTIINFLAMMATORY 4,5-DIARYLPYRROLES. 2. ACTIVITY AS A FUNCTION OF CYCLOOXYGENASE-2 INHIBITION", JOURNAL OF MEDICINAL CHEMISTRY, vol. 38, no. 20, 29 September 1995 (1995-09-29), pages 3895 - 3901, XP002030129
- [AD] THIAULT ET AL.: "N-Arylpyrrole derivatives with analgesic and antiinflammatory activities. Part I. 4,5-Disubstituted 1-arylpyrroles", FARMACO, ED. SCI., vol. 39, no. 6, 1984, pages 524 - 37, XP002059991
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
DOCDB simple family (application)
EP 03016556 A 19971209