EP 1370688 A1 20031217 - DETECTING INTERACTIONS BETWEEN OLIGONUCLEOTIDES AND RNA USING FLUORESCENCE RESONANCE ENERGY TRANSFER (FRET)
Title (en)
DETECTING INTERACTIONS BETWEEN OLIGONUCLEOTIDES AND RNA USING FLUORESCENCE RESONANCE ENERGY TRANSFER (FRET)
Title (de)
DETEKTION VON ABHÄNGIGKEITEN ZWISCHEN OLIGONUCLEOTIDES UND RNA MIT FLUORESZENZ-RESONANZ-ENERGIE-ÜBERTRAGUNG (FRET)
Title (fr)
DETECTION D'INTERACTIONS ENTRE OLIGONUCLEOTIDES ET ARN PAR TRANSFERT D'ENERGIE PAR RESONANCE DE FLUORESCENCE (FRET)
Publication
Application
Priority
- GB 0201016 W 20020307
- GB 0105789 A 20010308
Abstract (en)
[origin: WO02072885A1] There is provided a device and method for detecting interactions between oligonucleotides immobilised on a solid array and RNA that is added to the array. This detection of the interaction relies on Fluorescence Resonance Energy Transfer (FRET) between the two chromaphores. As the precise sequence of the immobilised oligonucleotides is known, it is therefore possible to determine structural parameters of native RNA transcripts and infer regions that may be effective targets for antisense mediated gene knock-down.
IPC 1-7
IPC 8 full level
C12Q 1/68 (2006.01); C12Q 1/6837 (2018.01)
CPC (source: EP)
C12Q 1/6837 (2013.01)
C-Set (source: EP)
Citation (search report)
See references of WO 02072885A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 02072885 A1 20020919; EP 1370688 A1 20031217; GB 0105789 D0 20010425
DOCDB simple family (application)
GB 0201016 W 20020307; EP 02704918 A 20020307; GB 0105789 A 20010308