Global Patent Index - EP 1370868 A2

EP 1370868 A2 20031217 - TECHNIQUE AND SCREENING METHOD FOR DETECTING REVERSIBLE PROTEIN-PROTEIN INTERACTIONS

Title (en)

TECHNIQUE AND SCREENING METHOD FOR DETECTING REVERSIBLE PROTEIN-PROTEIN INTERACTIONS

Title (de)

METHODE UND SCREENING-VERFAHREN ZUM NACHWEIS VON REVERSIBLEN PROTEIN-PROTEIN WECHSELWIRKUNGEN

Title (fr)

METHODE ET PROCEDE DE DEPISTAGE PERMETTANT DE DETECTER DES INTERACTIONS REVERSIBLES PROTEINE-PROTEINE

Publication

EP 1370868 A2 20031217 (DE)

Application

EP 01986933 A 20011221

Priority

  • DE 10064972 A 20001223
  • EP 0115265 W 20011221

Abstract (en)

[origin: WO02052272A2] The invention relates to methods and assays for detecting protein-protein interactions and for testing active substances in expression systems such as cells. According to the invention, protein I interacts with protein II, and a transfer of protein I into a cell compartment ensues, in which both protein I as well as protein II do not normally occur. When detecting protein II in the compartment, into which protein I was transferred, an interaction between protein I and protein II is determined.

IPC 1-7

G01N 33/68; A61K 47/48; G01N 33/50

IPC 8 full level

C40B 30/04 (2006.01); G01N 33/68 (2006.01)

CPC (source: EP)

C40B 30/04 (2013.01); G01N 33/6842 (2013.01); G01N 33/6845 (2013.01)

Citation (search report)

See references of WO 02052272A2

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

DOCDB simple family (publication)

WO 02052272 A2 20020704; WO 02052272 A3 20030710; AU 2002238479 A1 20020708; EP 1370868 A2 20031217

DOCDB simple family (application)

EP 0115265 W 20011221; AU 2002238479 A 20011221; EP 01986933 A 20011221