EP 1373501 A2 20040102 - TARGETING MOLECULES FOR ADENOVIRAL VECTORS
Title (en)
TARGETING MOLECULES FOR ADENOVIRAL VECTORS
Title (de)
ZIELGERICHTETE MOLEKÜLE FÜR ADNEOVIRALE VEKTOREN
Title (fr)
MOLECULES DE CIBLAGE POUR VECTEURS ADENOVIRAUX
Publication
Application
Priority
- EP 0111514 W 20011005
- US 68455200 A 20001006
- US 32756200 P 20001006
Abstract (en)
[origin: WO0229072A2] The present invention relates to targeting molecules which are useful to specifically target an adenoviral particle to a desired cell type. These targeting molecules comprise a soluble adenoviral receptor domain, a trimerization domain, and a targeting ligand domain. Further provided are polynucleotides encoding such targeting molecule, expression vectors including such polynucleotides, and methods to target an adenoviral particle to a cell, as well as methods to deliver a heterologous gene selectively to a cell.
IPC 1-7
C12N 15/12; C12N 15/62; C12N 15/86; C12N 15/47; C07K 14/705; A61K 48/00; G01N 33/50
IPC 8 full level
A61K 47/48 (2006.01); C07K 14/705 (2006.01); C12N 15/12 (2006.01); C12N 15/47 (2006.01); C12N 15/62 (2006.01); C12N 15/864 (2006.01); C12N 15/87 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01)
CPC (source: EP)
A61K 47/6901 (2017.07); C07K 14/705 (2013.01); C12N 15/62 (2013.01); C12N 15/86 (2013.01); C12N 15/87 (2013.01); A61K 35/13 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01); C07K 2319/00 (2013.01); C07K 2319/21 (2013.01); C07K 2319/32 (2013.01); C07K 2319/73 (2013.01); C12N 2710/10343 (2013.01); C12N 2710/10345 (2013.01); C12N 2810/405 (2013.01); C12N 2810/50 (2013.01); C12N 2810/859 (2013.01)
Citation (search report)
See references of WO 0229072A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0229072 A2 20020411; WO 0229072 A3 20031009; AU 2059302 A 20020415; CA 2424668 A1 20020411; EP 1373501 A2 20040102; IL 155139 A0 20031031
DOCDB simple family (application)
EP 0111514 W 20011005; AU 2059302 A 20011005; CA 2424668 A 20011005; EP 01986322 A 20011005; IL 15513901 A 20011005