EP 1377572 A1 20040107 - ISOXAXOLE DERIVATIVES AS INHIBITORS OF SRC AND OTHER PROTEIN KINASES
Title (en)
ISOXAXOLE DERIVATIVES AS INHIBITORS OF SRC AND OTHER PROTEIN KINASES
Title (de)
ISOXAZOL-DERIVATE ALS INHIBITOREN DER SRC UND ANDERER PROTEIN-KINASEN
Title (fr)
DERIVES D'ISOXAXOLE UTILISES COMME INHIBITEURS DE PROTEINES KINASES SRC ET D'AUTRES PROTEINES KINASES
Publication
Application
Priority
- US 0211609 W 20020410
- US 28293501 P 20010410
Abstract (en)
[origin: WO02083668A1] The present invention provides compounds of formula I: wherein A is N or CR, and R1, G and R2, are as described in the specification. These compounds are inhibitors of protein kinase, particularly inhibitors of Src mammalian protein kinase involved in cell proliferation, cell death and response to extracellular stimuli. The invention also relates to methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing those compositions in the treatment and prevention of various disorders.
IPC 1-7
C07D 413/14; A61K 31/505; C07D 413/04; C07D 417/14; A61K 31/4439; A61P 37/00; A61P 35/00
IPC 8 full level
A61K 31/4439 (2006.01); A61K 31/505 (2006.01); A61K 31/506 (2006.01); A61P 1/00 (2006.01); A61P 1/04 (2006.01); A61P 1/16 (2006.01); A61P 1/18 (2006.01); A61P 3/10 (2006.01); A61P 5/00 (2006.01); A61P 7/00 (2006.01); A61P 7/02 (2006.01); A61P 7/06 (2006.01); A61P 9/00 (2006.01); A61P 9/08 (2006.01); A61P 9/10 (2006.01); A61P 11/00 (2006.01); A61P 11/06 (2006.01); A61P 13/12 (2006.01); A61P 17/00 (2006.01); A61P 17/06 (2006.01); A61P 19/00 (2006.01); A61P 19/02 (2006.01); A61P 19/10 (2006.01); A61P 21/00 (2006.01); A61P 21/04 (2006.01); A61P 25/00 (2006.01); A61P 25/14 (2006.01); A61P 25/16 (2006.01); A61P 25/28 (2006.01); A61P 27/02 (2006.01); A61P 29/00 (2006.01); A61P 31/00 (2006.01); A61P 31/12 (2006.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01); A61P 37/00 (2006.01); A61P 37/02 (2006.01); A61P 37/08 (2006.01); A61P 43/00 (2006.01); C07D 413/04 (2006.01); C07D 413/14 (2006.01); C07D 417/14 (2006.01)
CPC (source: EP)
A61K 31/4439 (2013.01); A61K 31/505 (2013.01); A61P 1/00 (2017.12); A61P 1/04 (2017.12); A61P 1/16 (2017.12); A61P 1/18 (2017.12); A61P 3/10 (2017.12); A61P 5/00 (2017.12); A61P 7/00 (2017.12); A61P 7/02 (2017.12); A61P 7/06 (2017.12); A61P 9/00 (2017.12); A61P 9/08 (2017.12); A61P 9/10 (2017.12); A61P 11/00 (2017.12); A61P 11/06 (2017.12); A61P 13/12 (2017.12); A61P 17/00 (2017.12); A61P 17/06 (2017.12); A61P 19/00 (2017.12); A61P 19/02 (2017.12); A61P 19/10 (2017.12); A61P 21/00 (2017.12); A61P 21/04 (2017.12); A61P 25/00 (2017.12); A61P 25/14 (2017.12); A61P 25/16 (2017.12); A61P 25/28 (2017.12); A61P 27/02 (2017.12); A61P 29/00 (2017.12); A61P 31/00 (2017.12); A61P 31/12 (2017.12); A61P 35/00 (2017.12); A61P 35/02 (2017.12); A61P 37/00 (2017.12); A61P 37/02 (2017.12); A61P 37/08 (2017.12); A61P 43/00 (2017.12); C07D 413/04 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01)
Citation (search report)
See references of WO 02083668A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 02083668 A1 20021024; CA 2443234 A1 20021024; EP 1377572 A1 20040107; JP 2005500261 A 20050106; MX PA03009257 A 20040129
DOCDB simple family (application)
US 0211609 W 20020410; CA 2443234 A 20020410; EP 02731356 A 20020410; JP 2002581423 A 20020410; MX PA03009257 A 20020410