EP 1383517 A1 20040128 - USE OF CATIONIC DEXTRAN DERIVATIVES FOR PROTECTING DOSE-LIMITING ORGANS
Title (en)
USE OF CATIONIC DEXTRAN DERIVATIVES FOR PROTECTING DOSE-LIMITING ORGANS
Title (de)
VERWENDUNG VON KATIONISCHEN DEXTRANDERIVATIVEN ZUM SCHUTZ DOSISBEGRENZENDER ORGANE
Title (fr)
UTILISATION DE DERIVES CATIONIQUES DU DEXTRANE POUR PROTEGER LES ORGANES A LIMITATION DE DOSE
Publication
Application
Priority
- FI 0200305 W 20020411
- FI 20010764 A 20010411
Abstract (en)
[origin: WO02083154A1] The present invention discloses the use of cationic dextran derivatives provided with substituents having positively charged side groups as protective agents for dosage limiting organs in systemic treatment of diseases including cancer. The cationic dextran derivatives are particularly useful nephroprotective agents for a subject receiving systemic treatment with cytostatic pharmaceuticals, compounds carrying cytostatic pharmaceuticals, radionuclides or compounds carrying radionuclides against renal damage. The cationic dextran derivatives not only protect the dose-limiting organs but are better tolerated and have less side effects than conventionally used protective agents.
IPC 1-7
IPC 8 full level
A61K 31/721 (2006.01); A61P 13/12 (2006.01); A61P 35/00 (2006.01); C08B 37/02 (2006.01)
CPC (source: EP KR)
A61K 31/721 (2013.01 - EP KR); A61P 13/12 (2018.01 - EP); A61P 35/00 (2018.01 - EP); C08B 37/0021 (2013.01 - EP)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 02083154 A1 20021024; BR 0208860 A 20041019; CA 2443052 A1 20021024; EE 200300502 A 20031215; EP 1383517 A1 20040128; FI 20010764 A0 20010411; HU P0401386 A2 20041228; HU P0401386 A3 20050628; IL 158153 A0 20040328; JP 2004525181 A 20040819; KR 20040018350 A 20040303; NO 20034561 D0 20031010; NO 20034561 L 20031209; PL 363024 A1 20041115; RU 2003132683 A 20050410
DOCDB simple family (application)
FI 0200305 W 20020411; BR 0208860 A 20020411; CA 2443052 A 20020411; EE P200300502 A 20020411; EP 02714245 A 20020411; FI 20010764 A 20010411; HU P0401386 A 20020411; IL 15815302 A 20020411; JP 2002580956 A 20020411; KR 20037013284 A 20031010; NO 20034561 A 20031010; PL 36302402 A 20020411; RU 2003132683 A 20020411