EP 1383928 A1 20040128 - NEW METHOD
Title (en)
NEW METHOD
Title (de)
NEUES VERFAHREN
Title (fr)
PROCEDE
Publication
Application
Priority
- SE 0200677 W 20020404
- SE 0101218 A 20010405
- US 28138401 P 20010405
Abstract (en)
[origin: WO02081748A1] The invention concerns a method for identifying RNA-binding molecules, comprising the steps of: predicting the structure of an RNA-fragment by an in silico method, choosing a suitable predicted RNA-fragment, synthesizing the cDNA-fragment corresponding to the predicted RNA-fragment, inserting the cDNA-fragment in the upstream proximity of a reporter assay gene, which reporter assay gene produces a signal upon translation, thereby forming a reporter construct, and performing a reporter gene assay, which assay monitors the interaction between a molecule to be tested for RNA-binding and the RNA-fragment of the reporter construct. Furthermore, the invention relates to the use of specific RNA-fragments in the method of the invention.
IPC 1-7
IPC 8 full level
C12N 15/10 (2006.01); C12Q 1/68 (2006.01)
CPC (source: EP)
C12N 15/1034 (2013.01); C12Q 1/6811 (2013.01)
C-Set (source: EP)
Citation (search report)
See references of WO 02081748A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 02081748 A1 20021017; CA 2440845 A1 20021017; EP 1383928 A1 20040128
DOCDB simple family (application)
SE 0200677 W 20020404; CA 2440845 A 20020404; EP 02759844 A 20020404