Global Patent Index - EP 1386001 A4

EP 1386001 A4 20050720 - KITS AND METHODS FOR ASSESSING OXIDATIVE STRESS

Title (en)

KITS AND METHODS FOR ASSESSING OXIDATIVE STRESS

Title (de)

KITS UND VERFAHREN ZUR BEURTEILUNG VON OXIDATIVEM STRESS

Title (fr)

TROUSSES ET METHODES PERMETTANT D'EVALUER LE STRESS OXYDATIF

Publication

EP 1386001 A4 20050720 (EN)

Application

EP 02736545 A 20020405

Priority

  • US 0210682 W 20020405
  • US 82652201 A 20010405
  • US 28916901 P 20010507
  • US 35051701 P 20011022
  • US 33542601 P 20011024
  • US 33681501 P 20011205

Abstract (en)

[origin: WO02080755A2] The invention relates to kits and methods for assessing the susceptibility of a human to oxidative stress or damage. The methods involve assessing occurrence in the human's genome of one or more polymorphisms (e.g., single nucleotide polymorphisms) that occur in one or more genes associated with oxidative stress and that are associated with a disorder in humans. Preferred assessment and scoring methods are disclosed, as are kits for performing the methods.

IPC 1-7

C12Q 1/68; C12P 19/34; C07H 21/04

IPC 8 full level

C12N 15/09 (2006.01); C12Q 1/68 (2006.01)

CPC (source: EP)

C12Q 1/6883 (2013.01); C12Q 2600/156 (2013.01)

Citation (search report)

  • [XY] AMBROSONE CHRISTINE B ET AL: "Manganese superoxide dismutase (MnSOD) genetic polymorphisms, dietary antioxidants, and risk of breast cancer", CANCER RESEARCH, AMERICAN ASSOCIATION FOR CANCER RESEARCH, BALTIMORE, MD, US, vol. 59, no. 3, 1 February 1999 (1999-02-01), pages 602 - 606, XP002200091, ISSN: 0008-5472
  • [PX] HONG YUN-CHUL ET AL: "Genetic susceptibility of term pregnant women to oxidative damage", TOXICOLOGY LETTERS (SHANNON), vol. 129, no. 3, March 2002 (2002-03-01), pages 255 - 262, XP002313547, ISSN: 0378-4274
  • [Y] MATSUI A ET AL: "Increased formation of oxidative DNA damage, 8-hydroxy-2'-deoxyguanosine, in human breast cancer tissue and its relationship to GSTP1 and COMT genotypes", CANCER LETTERS, NEW YORK, NY, US, vol. 151, no. 1, 3 April 2000 (2000-04-03), pages 87 - 95, XP002223706, ISSN: 0304-3835
  • [A] BORGSTAHL GLORIA E O ET AL: "Human mitochondrial manganese superoxide dismutase polymorphic variant Ile58Thr reduces activity by destabilizing the tetrameric interface", BIOCHEMISTRY, vol. 35, no. 14, 1996, pages 4287 - 4297, XP002313548, ISSN: 0006-2960
  • See references of WO 02080755A2

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

DOCDB simple family (publication)

WO 02080755 A2 20021017; WO 02080755 A3 20031030; WO 02080755 A9 20030306; AU 2002309543 B2 20050623; CA 2443395 A1 20021017; EP 1386001 A2 20040204; EP 1386001 A4 20050720; JP 2004528840 A 20040924

DOCDB simple family (application)

US 0210682 W 20020405; AU 2002309543 A 20020405; CA 2443395 A 20020405; EP 02736545 A 20020405; JP 2002578795 A 20020405