EP 1389233 A4 20060308 - ANTI-RANK LIGAND MONOCLONAL ANTIBODIES USEFUL IN TREATMENT OF RANK LIGAND MEDIATED DISORDERS
Title (en)
ANTI-RANK LIGAND MONOCLONAL ANTIBODIES USEFUL IN TREATMENT OF RANK LIGAND MEDIATED DISORDERS
Title (de)
ZUR BEHANDLUNG VON DURCH RANK-LIGAND-VERMITTELTEN ERKRANKUNGEN GEEIGNETE MONOKLONALE ANTIKÖRPER GEGEN RANK-LIGAND
Title (fr)
ANTICORPS MONOCLONAUX A LIGANDS ANTI-RANK CONVENANT AU TRAITEMENT DE TROUBLES INDUITS PAR DES LIGANDS RANK
Publication
Application
Priority
- US 0214246 W 20020503
- US 29203101 P 20010518
Abstract (en)
[origin: WO02095012A1] Chimeric, humanized and other RANK-L mAbs, derived from high affinity neutralizing mAbs, pharmaceutical compositions containing same, method of treatment and diagnostics are provided.
IPC 8 full level
C12N 5/06 (2006.01); C12N 15/09 (2006.01); A61K 39/395 (2006.01); A61P 1/04 (2006.01); A61P 3/10 (2006.01); A61P 19/02 (2006.01); A61P 19/08 (2006.01); A61P 19/10 (2006.01); A61P 25/28 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01); A61P 35/04 (2006.01); A61P 37/00 (2006.01); C07H 21/04 (2006.01); C07K 16/00 (2006.01); C07K 16/24 (2006.01); C07K 16/28 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12P 21/08 (2006.01); G01N 33/53 (2006.01); G01N 33/68 (2006.01)
CPC (source: EP)
A61P 1/04 (2017.12); A61P 3/10 (2017.12); A61P 19/02 (2017.12); A61P 19/08 (2017.12); A61P 19/10 (2017.12); A61P 25/28 (2017.12); A61P 29/00 (2017.12); A61P 35/00 (2017.12); A61P 35/04 (2017.12); A61P 37/00 (2017.12); C07K 16/2875 (2013.01); G01N 33/6863 (2013.01); A61K 2039/505 (2013.01)
Citation (search report)
- [PY] WO 0191793 A1 20011206 - SMITHKLINE BEECHAM CORP [US], et al
- [PY] WO 0215846 A2 20020228 - SMITHKLINE BEECHAM CORP [US], et al
- [Y] TANAKA Y ET AL: "INTERCELLULAR ADHESION MOLECULE 1 DISCRIMINATES FUNCTIONALLY DIFFERENT POPULATIONS OF HUMAN OSTEOBLASTS: CHARACTERISTIC INVOLVEMENT OF CELL CYCLE REGULATORS", JOURNAL OF BONE AND MINERAL RESEARCH, NEW YORK, NY, US, vol. 15, no. 10, October 2000 (2000-10-01), pages 1912 - 1923, XP009030306, ISSN: 0884-0431
- [Y] MENAA C ET AL: "Enhanced RANK ligand expression and responsivity of bone marrow cells in Paget's disease of bone", JOURNAL OF CLINICAL INVESTIGATION, NEW YORK, NY, US, vol. 105, no. 12, June 2000 (2000-06-01), pages 1833 - 1838, XP002278692, ISSN: 0021-9738
- [Y] NAGAI MASAZUMI ET AL: "Cancer cells responsible for humoral hypercalcemia express mRNA encoding a secreted form of ODF/TRANCE that induces osteoclast formation", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 269, no. 2, 16 March 2000 (2000-03-16), pages 532 - 536, XP002278694, ISSN: 0006-291X
- See references of WO 02095012A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 02095012 A1 20021128; EP 1389233 A1 20040218; EP 1389233 A4 20060308; JP 2005515752 A 20050602
DOCDB simple family (application)
US 0214246 W 20020503; EP 02736659 A 20020503; JP 2002592475 A 20020503