EP 1390052 A4 20081008 - INHIBITION OF JUN KINASE
Title (en)
INHIBITION OF JUN KINASE
Title (de)
HEMMUNG VON JUN KINASE
Title (fr)
INHIBITION DE LA KINASE JUN
Publication
Application
Priority
- US 0212687 W 20020424
- US 28596601 P 20010424
Abstract (en)
[origin: WO02085396A1] A method of treating a metabolic disorder associated with insulin resistance by administering to a mammal an inhibitor of a NH2-terminal Jun Kinase (JNK), e.g., a compound or peptide which inhibits JNK1 expression or enzymatic activity.
IPC 1-7
IPC 8 full level
A61K 38/45 (2006.01)
CPC (source: EP)
A61K 38/45 (2013.01); A61P 3/04 (2017.12); A61P 3/10 (2017.12); A61P 5/50 (2017.12)
Citation (search report)
- [X] WO 9953927 A1 19991028 - TUFTS COLLEGE [US], et al
- [Y] AGUIRRE V; UCHIDA T; YENUSH L; DAVIS R; WHITE M F: "The c-Jun NH2-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser307", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 275, no. 12, 24 March 2000 (2000-03-24), pages 9047 - 9054, XP002493212, ISSN: 0021-9258
- [Y] BENNETT B ET AL: "A SELECTIVE INHIBITOR OF JNK THAT MODULATES THE ACTIVATION AND DIFFERENTIATION OF CD4+ CELLS", IMFLAMMATION RESEARCH, BIRKHAEUSER VERLAG, BASEL, vol. 49, no. SUPPL. 02, 1 August 2000 (2000-08-01), pages S102, XP008014580, ISSN: 1023-3830
- See references of WO 02085396A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 02085396 A1 20021031; CA 2477842 A1 20021031; EP 1390052 A1 20040225; EP 1390052 A4 20081008
DOCDB simple family (application)
US 0212687 W 20020424; CA 2477842 A 20020424; EP 02764295 A 20020424