Global Patent Index - EP 1390382 A4

EP 1390382 A4 2007-10-31 - ELUCIDATION OF GENE FUNCTION

Title (en)

ELUCIDATION OF GENE FUNCTION

Title (de)

AUFKLÄRUNG VON GENFUNKTION

Title (fr)

ELUCIDATION DE LA FONCTION DE GENES

Publication

EP 1390382 A4 (EN)

Application

EP 02729046 A

Priority

  • US 0213432 W
  • US 28733501 P

Abstract (en)

[origin: WO02088165A1] Articles and methods are provided for determining the function of genes in a rapid and cost effective manner. Nucleic acids are arrayed upon a substrate. In accordance with certain preferred embodiments, viable cells are subsequently caused to be bound to the substrate at the locations occupied by the nucleic acids. Subsequent transduction or transfection of the cells by the nucleic acids followed by continued vitality of the cells permits expression of the proteins encoded by the respected nucleic acids. Knowledge of the identity of the nucleic acids, at least as regards their locations on the substrate, permits determination of protein function thereof. Methods of creating and using such cell-arrays, and methods of reverse-transfection and reverse-transduction are featured.

IPC 1-7 (main, further and additional classification)

C12N 15/10; C07H 21/04; C12Q 1/68; G01N 33/68

IPC 8 full level (invention and additional information)

C07H 21/04 (2006.01); C12N 15/10 (2006.01); C12Q 1/68 (2006.01)

CPC (invention and additional information)

C12N 15/1034 (2013.01)

Citation (search report)

  • [X] SIMONSEN H ET AL: "CLONING BY FUNCTION: EXPRESSION CLONING IN MAMMALIAN CELLS", TRENDS IN PHARMACOLOGICAL SCIENCES, ELSEVIER, HAYWARTH, GB, vol. 15, no. 12, December 1994 (1994-12-01), pages 437 - 441, XP001084196, ISSN: 0165-6147
  • [A] SCHENA M ET AL: "QUANTITATIVE MONITORING OF GENE EXPRESSION PATTERNS WITH A COMPLEMENTARY DNAMICROARRAY", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 270, no. 5235, 20 October 1995 (1995-10-20), pages 467 - 470, XP000644675, ISSN: 0036-8075
  • [A] MACBEATH G ET AL: "Printing proteins as microarrays for high-throughput function determination", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 289, no. 5485, 8 September 2000 (2000-09-08), pages 1760 - 1763, XP002279793, ISSN: 0036-8075
  • [PX] ZIAUDDIN J ET AL: "Microarrays of cells expressing defined cDNAs", NATURE, NATURE PUBLISHING GROUP, LONDON, GB, vol. 411, 3 May 2001 (2001-05-03), pages 107 - 110, XP002963625, ISSN: 0028-0836
  • See also references of WO 02088165A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

EPO simple patent family

WO 02088165 A1 20021107; CA 2445884 A1 20021107; EP 1390382 A1 20040225; EP 1390382 A4 20071031

INPADOC legal status


2012-04-25 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20111101

2011-08-17 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20110713

2007-10-31 [A4] SUPPLEMENTARY SEARCH REPORT

- Effective date: 20070928

2007-08-08 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: C12N 15/10 20060101AFI20070629BHEP

2007-08-08 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: C12Q 1/68 20060101ALI20070629BHEP

2007-08-08 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: G01N 33/68 20060101ALI20070629BHEP

2007-08-08 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: C07H 21/04 20060101ALI20070629BHEP

2004-02-25 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20031119

2004-02-25 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

2004-02-25 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Countries: AL LT LV MK RO SI