EP 1392265 A2 20040303 - INHIBITORS OF ABC DRUG TRANSPORTERS AT THE BLOOD-BRAIN BARRIER
Title (en)
INHIBITORS OF ABC DRUG TRANSPORTERS AT THE BLOOD-BRAIN BARRIER
Title (de)
INHIBITOREN VON ABC ARZNEIMITTEL TRANSPORTERN IN DER BLUT-HIRN-SCHRANKE
Title (fr)
INHIBITEURS DES TRANSPORTEURS DU MEDICAMENT D'ABC AU NIVEAU DE LA BARRIERE HEMATO-ENCEPHALIQUE
Publication
Application
Priority
- US 0145367 W 20011030
- US 24448200 P 20001030
- US 24511000 P 20001101
- US 24623500 P 20001102
Abstract (en)
[origin: WO0241884A2] The present invention relates to inhibitors of drug transporters of the ABC protein superfamily, particularly transporters present at the blood brain barrier. ABC transporter inhibitors identified according to the invention increase brain concentrations of CNS-active agents. Such inhibitors increase the influx into the brain and/or reduce the efflux from the brain of such CNS-active agents.
IPC 1-7
IPC 8 full level
A61K 9/20 (2006.01); A61K 9/48 (2006.01); A61K 9/50 (2006.01); A61K 31/00 (2006.01); A61K 31/137 (2006.01); A61K 31/445 (2006.01); A61K 31/485 (2006.01); A61K 45/06 (2006.01); A61P 1/10 (2006.01); A61P 25/04 (2006.01); A61P 25/26 (2006.01); A61P 29/00 (2006.01); A61P 43/00 (2006.01); A61K 31/135 (2006.01)
CPC (source: EP)
A61K 9/2018 (2013.01); A61K 9/2054 (2013.01); A61K 9/4858 (2013.01); A61K 9/4866 (2013.01); A61K 9/5042 (2013.01); A61K 9/5084 (2013.01); A61K 31/00 (2013.01); A61K 31/135 (2013.01); A61K 31/445 (2013.01); A61K 31/485 (2013.01); A61K 45/06 (2013.01); A61P 1/10 (2017.12); A61P 25/04 (2017.12); A61P 25/26 (2017.12); A61P 29/00 (2017.12); A61P 43/00 (2017.12)
Citation (search report)
See references of WO 0241884A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0241884 A2 20020530; WO 0241884 A8 20031211; AU 3942702 A 20020603; CA 2427330 A1 20020530; EP 1392265 A2 20040303; JP 2004528273 A 20040916
DOCDB simple family (application)
US 0145367 W 20011030; AU 3942702 A 20011030; CA 2427330 A 20011030; EP 01987187 A 20011030; JP 2002544063 A 20011030